APC-6860

Name: APC-6860
Brand: TargetMol
SKU: T39029
Price: 297 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T39029Cas号 154628-42-9

APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA versus uPA of 80. APC-6860 has k i values of 0.1, 0.082 μM for human and murine urokinases, respectively. APC-6860 can be used for the research of cancer.

APC-6860

还可以

产品编号 T39029Cas号 154628-42-9

规格	价格	库存	数量
25 mg	¥ 10,600	6-8周

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生物活性

产品描述	APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA versus uPA of 80. APC-6860 has k i values of 0.1, 0.082 μM for human and murine urokinases, respectively. APC-6860 can be used for the research of cancer.
靶点活性	Thrombin:20 μM (Ki), Urokinases (murine):0.082 μM (Ki), FXa:30 μM (Ki), Urokinases (human):0.1 μM (Ki), uPA:0.21 μM (Ki), Tryptase:1.5 μM (Ki), Trypsin:0.44 μM (Ki), TPA:16.8 μM (Ki)
体外活性	APC-6860 (compounds 2) inhibits urokinases in MiaPaCa-2 and Lewis Lung Carcinoma cells with IC 50 s of 1.4 and 3.1 μM, respectively[2].