FATP1-IN-1 is a potent inhibitor of fatty acid transport protein 1 (FATP1). It effectively inhibits the activity of recombinant human or mouse acyl-CoA synthetase, which is essential for the function of FATP1. The inhibition is characterized by IC50 values of 0.046 μM for human FATP1 and 0.60 μM for mouse FATP1.

FATP1-IN-1 (口服；10 mg/kg) 的治疗展现了其最大浓度（Cmax）为5.5 μg/mL，面积下曲线（AUC）为36 μg h/mL，达到最大浓度的时间（Tmax）为0.33小时，均超过小鼠半抑制浓度（IC50）0.22 μM。动物模型：小鼠血浆[1]。剂量：10 mg/kg。给药方式：口服。结果显示，最大浓度（Cmax）、面积下曲线（AUC）和达到最大浓度的时间（Tmax）分别为5.5 μg/mL、36 μg h/mL和0.33小时。