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CDK5R1 Protein, Human, Recombinant (His)

产品编号 TMPH-01170

CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli.

CDK5R1 Protein, Human, Recombinant (His)

CDK5R1 Protein, Human, Recombinant (His)

产品编号 TMPH-01170
CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli.
规格价格库存数量
20 μg¥ 1,80020日内发货
100 μg¥ 3,42020日内发货
1 mg¥ 14,60020日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。

产品信息

生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli.
种属
Human
表达系统
E. coli
标签N-6xHis
蛋白编号Q15078
别名
TPKII regulatory subunit,NCK5A,Cyclin-dependent kinase 5 regulatory subunit 1,Cyclin-dependent kinase 5 activator 1,CDK5R1,CDK5R,CDK5 activator 1
氨基酸序列
AQPPPAQPPAPPASQLSGSQTGGSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR
蛋白构建
99-307 aa
蛋白纯度
> 85% as determined by SDS-PAGE.
分子量27.3 kDa (predicted)
缓冲液If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法
Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

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