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FGF-21 Protein, Human, Recombinant

FGF-21 Protein, Human, Recombinant

产品编号 TMPY-06935
别名: 成纤维细胞生长因子, UNQ3115 / PRO10196, fibroblast growth factor 21

FGF-21 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.55 kDa and the accession number is NP_061986.1.

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FGF-21 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
50 μg ¥ 2,430 现货
100 μg ¥ 4,310 5日内发货
200 μg ¥ 7,620 5日内发货
500 μg ¥ 16,130 5日内发货
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产品目录号及名称: FGF-21 Protein, Human, Recombinant (TMPY-06935)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.1-0.6 µg/mL in the presence of Recombinant Mouse Klotho beta.

TargetMol Bioactive

产品描述 FGF-21 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.55 kDa and the accession number is NP_061986.1.
种属 Human
表达系统 E. coli
标签 Tag Free
蛋白编号 NP_061986.1
别名 成纤维细胞生长因子, UNQ3115 / PRO10196, fibroblast growth factor 21
蛋白构建 Human FGF21 (NP_061986.1) (His29-Ser209)
蛋白纯度 ≥ 95 % as determined by SDS-PAGE.

TargetMol

分子量 19.55 kDa (predicted)
内毒素 < 10 EU/mg of the protein.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

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Keywords

FGF-21 Protein, Human, Recombinant 成纤维细胞生长因子 UNQ3115 / PRO10196 fibroblast growth factor 21 UNQ3115 / PRO-10196 UNQ3115 / PRO 10196 recombinant recombinant-proteins proteins protein

 

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