Name: GNMT Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01118
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 693

2-4周

10 μg

¥ 1,170

2-4周

20 μg

¥ 1,860

2-4周

50 μg

¥ 3,470

2-4周

100 μg

¥ 4,930

2-4周

200 μg

¥ 7,350

2-4周

500 μg

¥ 12,100

2-4周

1 mg

¥ 17,300

2-4周

生物活性

产品描述	Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
种属	Human
表达系统	E. coli
标签	N-6xHis
蛋白编号	Q14749
氨基酸序列	Met1-Asp295
蛋白构建	Met1-Asp295
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
别名	GNMT, Glycine N-Methyltransferase
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.