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RBM14 Protein, Human, Recombinant (His & SUMO)

RBM14 Protein, Human, Recombinant (His & SUMO)

产品编号 TMPH-02053
别名: RNA-binding protein 14, RRM-containing coactivator activator/modulator, RNA-binding motif protein 14, Synaptotagmin-interacting protein, RBM14, Paraspeckle protein 2

RBM14 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

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RBM14 Protein, Human, Recombinant (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: RBM14 Protein, Human, Recombinant (His & SUMO) (TMPH-02053)
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生物活性
技术参数
产品性质
产品描述 RBM14 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-6xHis-SUMO
蛋白编号 Q96PK6
别名 RNA-binding protein 14, RRM-containing coactivator activator/modulator, RNA-binding motif protein 14, Synaptotagmin-interacting protein, RBM14, Paraspeckle protein 2
氨基酸序列 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM
蛋白构建 1-669 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 85.5 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.

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Keywords

RBM14 Protein, Human, Recombinant (His & SUMO) RNA-binding protein 14 RRM-containing coactivator activator/modulator RNA-binding motif protein 14 Synaptotagmin-interacting protein RBM14 Paraspeckle protein 2 recombinant recombinant-proteins proteins protein

 

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