Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 1,320 | 20日内发货 | ||
100 μg | ¥ 2,470 | 20日内发货 | ||
1 mg | ¥ 10,700 | 20日内发货 |
产品描述 | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
种属 | Human |
表达系统 | E. coli |
标签 | N-10xHis-SUMO, C-Myc |
蛋白编号 | Q7LBC6 |
别名 | [histone H3]-dimethyl-L-lysine(9) demethylase 3B, Lysine-specific demethylase 3B, JmjC domain-containing histone demethylation protein 2B, KDM3B, Nuclear protein 5qNCA, Jumonji domain-containing protein 1B |
氨基酸序列 | MPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFR |
蛋白构建 | 1498-1721 aa |
蛋白纯度 | > 90% as determined by SDS-PAGE. |
分子量 | 45.6 kDa (predicted) |
缓冲液 | Tris-based buffer, 50% glycerol |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
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KDM3B Protein, Human, Recombinant (His & Myc & SUMO) [histone H3]-dimethyl-L-lysine(9) demethylase 3B Lysine-specific demethylase 3B JmjC domain-containing histone demethylation protein 2B KDM3B Nuclear protein 5qNCA Jumonji domain-containing protein 1B recombinant recombinant-proteins proteins protein