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Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 2,120 | 5日内发货 | |
25 mg | ¥ 11,000 | 10-14周 | |
50 mg | ¥ 14,300 | 10-14周 | |
100 mg | ¥ 21,800 | 10-14周 |
产品描述 | Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5. |
靶点活性 | HIV-1 (MOKW):0.2 nM (IC50), HIV-1 (JRFL):0.1 nM (IC50), HIV-1 (Ba-L):0.4 nM (IC50) |
别名 | GW873140A, GW-873140, GW873140, Aplaviroc HCl, AK-602, AK602, AK 602 |
分子量 | 614.17 |
分子式 | C33H44ClN3O6 |
CAS No. | 461023-63-2 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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