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pUL89 Endonuclease-IN-1 (Compound 13d) 是人巨细胞病毒 (HCMV) pUL89 核酸内切酶的有效抑制剂,IC50值为 0.88 μM,具有抗病毒活性。
pUL89 Endonuclease-IN-1 (Compound 13d) 是人巨细胞病毒 (HCMV) pUL89 核酸内切酶的有效抑制剂,IC50值为 0.88 μM,具有抗病毒活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | |
50 mg | ¥ 13,800 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | pUL89 Endonuclease-IN-1 (Compound 13d), with an IC50 value of 0.88 μM, serves as a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease, demonstrating antiviral activity [1]. |
体外活性 | pUL89 Endonuclease-IN-1 (compound 13d) strongly inhibits pUL89-C with the values of IC 50 0.88μM. pUL89 Endonuclease-IN-1 reveals excellent aqueous solubility, plasma stability, and metabolic stability in vitro ADME. pUL89 Endonuclease-IN-1 displays moderately permeability in the PAMPA [1]. Cell Cytotoxicity Assay [1] Cell Line: HFF cells Concentration: 5 μM Incubation Time: 168 h Result: Showed significant inhibition for HCMV at 5 μM. |
分子量 | 252.25 |
分子式 | C10H8N2O4S |
CAS No. | 391680-92-5 |
存储 | Shipping with blue ice. |
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