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ASXL1 Protein, Human, Recombinant (GST)

ASXL1 Protein, Human, Recombinant (GST)

产品编号 TMPJ-01213
别名: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, KIAA0978, ASXL1

Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

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ASXL1 Protein, Human, Recombinant (GST)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 13,200 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: ASXL1 Protein, Human, Recombinant (GST) (TMPJ-01213)
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产品描述 Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
种属 Human
表达系统 E. coli
标签 N-GST
蛋白编号 Q8IXJ9
别名 Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, KIAA0978, ASXL1
氨基酸序列 Lys1477-Arg1541
蛋白构建 Lys1477-Arg1541
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 38 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

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Keywords

ASXL1 Protein, Human, Recombinant (GST) KIAA 0978 Putative Polycomb group protein ASXL1 Additional sex combs-like protein 1 KIAA0978 KIAA-0978 ASXL1 ASXL-1 ASXL 1 recombinant recombinant-proteins proteins protein

 

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