您的购物车当前为空
别名 α-crystallin C chain, Small stress protein-like protein HSP22, Protein kinase H11, HspB8, HSP22, Heat shock protein β-8, Heat shock protein beta-8, E2-induced gene 1 protein, E2IG1, CRYAC, Alpha-crystallin C chain
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.


为众多的药物研发团队赋能,
让新药发现更简单!
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 693 | 6-8日内发货 | |
| 10 μg | ¥ 1,170 | 6-8日内发货 | |
| 20 μg | ¥ 1,860 | 5日内发货 | |
| 50 μg | ¥ 3,470 | 5日内发货 | |
| 100 μg | ¥ 4,930 | 5日内发货 | |
| 200 μg | ¥ 7,350 | 5日内发货 | |
| 500 μg | ¥ 12,100 | 5日内发货 | |
| 1 mg | ¥ 18,900 | 5日内发货 |
| 产品描述 | Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | C-6xHis |
| 蛋白编号 | Q9UJY1 |
| 氨基酸序列 | Met1-Thr196 |
| 蛋白构建 | Met1-Thr196 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 mM EDTA, pH 7.4. |
| 别名 | α-crystallin C chain, Small stress protein-like protein HSP22, Protein kinase H11, HspB8, HSP22, Heat shock protein β-8, Heat shock protein beta-8, E2-induced gene 1 protein, E2IG1, CRYAC, Alpha-crystallin C chain |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 23 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
对于不同动物的给药剂量换算,您也可以参考 更多