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U18666A 是一种细胞渗透性药物,是一种胆固醇合成和转运抑制剂,抑制埃博拉病毒,登革热病毒和人类丙型肝炎病毒的复制。
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U18666A 是一种细胞渗透性药物,是一种胆固醇合成和转运抑制剂,抑制埃博拉病毒,登革热病毒和人类丙型肝炎病毒的复制。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 263 | 现货 | |
2 mg | ¥ 383 | 现货 | |
5 mg | ¥ 652 | 现货 | |
10 mg | ¥ 987 | 现货 | |
25 mg | ¥ 1,880 | 现货 | |
50 mg | ¥ 2,950 | 现货 | |
100 mg | ¥ 4,350 | 现货 | |
200 mg | ¥ 6,150 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 721 | 现货 |
产品描述 | U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus. |
体外活性 | U18666A, the antiviral effect is found to result from retarded viral trafficking in the cholesterol-loaded late endosomes/lysosomes and suppressed de novo sterol biosynthesis in treated infected cells. It is also observed an additive antiviral effect of U18666A with C75, a fatty acid synthase inhibitor [1][2]. |
分子量 | 424.06 |
分子式 | C25H42ClNO2 |
CAS No. | 3039-71-2 |
Smiles | Cl.[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OCCN(CC)CC |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (117.91 mM), Sonication is recommended. H2O: 10 mg/mL (23.58 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
|
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