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COX5A Protein, Human, Recombinant (GST)

COX5A Protein, Human, Recombinant (GST)

产品编号 TMPH-01180
别名: Cytochrome c oxidase polypeptide Va, Cytochrome c oxidase subunit 5A, mitochondrial, COX5A

COX5A Protein, Human, Recombinant (GST) is expressed in E. coli.

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COX5A Protein, Human, Recombinant (GST)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: COX5A Protein, Human, Recombinant (GST) (TMPH-01180)
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生物活性
技术参数
产品性质
产品描述 COX5A Protein, Human, Recombinant (GST) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-GST
蛋白编号 P20674
别名 Cytochrome c oxidase polypeptide Va, Cytochrome c oxidase subunit 5A, mitochondrial, COX5A
氨基酸序列 SHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV
蛋白构建 42-150 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 39.5 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

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Keywords

COX5A Protein, Human, Recombinant (GST) Cytochrome c oxidase polypeptide Va Cytochrome c oxidase subunit 5A, mitochondrial COX5A recombinant recombinant-proteins proteins protein

 

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