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HDAC9 Protein, Human, Recombinant (His)

HDAC9 Protein, Human, Recombinant (His)

产品编号 TMPH-01476
别名: HDAC9, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, Histone deacetylase 7B, Histone deacetylase 9

HDAC9 Protein, Human, Recombinant (His) is expressed in E. coli.

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HDAC9 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: HDAC9 Protein, Human, Recombinant (His) (TMPH-01476)
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生物活性
技术参数
产品性质
产品描述 HDAC9 Protein, Human, Recombinant (His) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-6xHis
蛋白编号 Q9UKV0
别名 HDAC9, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, Histone deacetylase 7B, Histone deacetylase 9
氨基酸序列 ILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSMSLKFS
蛋白构建 814-1011 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 25.2 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.; Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.

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Keywords

HDAC9 Protein, Human, Recombinant (His) HDAC9 Histone deacetylase-related protein MEF2-interacting transcription repressor MITR Histone deacetylase 7B Histone deacetylase 9 recombinant recombinant-proteins proteins protein

 

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