Name: Fradafiban
Brand: TargetMol
SKU: T11322
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

¥ 12,800

10-14周

50 mg

¥ 16,800

10-14周

100 mg

¥ 21,500

10-14周

生物活性

产品描述	Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
靶点活性	GP IIb/IIIa complex (human platelet):(kd)148 nM
体外活性	Fradafiban binds with high affinity and selectivity to the human platelet GP IIb/IIIa complex and potently inhibits human platelet aggregation in vitro.?Fradafiban reversibly binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.?Fradafiban is a nonpeptide mimetic of the arginine-glycine-aspartic acid recognition sequence.
体内活性	Fradafiban has only very limited oral activity probably due to its high polarity and thus poor absorption after oral ingestion.
别名	BIBU-52

化学信息

分子量	367.40
分子式	C₂₀H₂₁N₃O₄
CAS No.	148396-36-5
Smiles	O(C[C@@H]1C[C@@H](CC(O)=O)C(=O)N1)C2=CC=C(C=C2)C3=CC=C(C(=N)N)C=C3
密度	1.38g/cm3

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.

Fradafiban