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Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist. |
靶点活性 | GP IIb/IIIa complex (human platelet):(kd)148 nM |
体外活性 | Fradafiban binds with high affinity and selectivity to the human platelet GP IIb/IIIa complex and potently inhibits human platelet aggregation in vitro.?Fradafiban reversibly binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.?Fradafiban is a nonpeptide mimetic of the arginine-glycine-aspartic acid recognition sequence. |
体内活性 | Fradafiban has only very limited oral activity probably due to its high polarity and thus poor absorption after oral ingestion. |
别名 | BIBU-52 |
分子量 | 367.4 |
分子式 | C20H21N3O4 |
CAS No. | 148396-36-5 |
密度 | 1.38g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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