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EIF5A Protein, Human, Recombinant (His)

产品编号 TMPY-04108

别名: EIF5A1, eukaryotic translation initiation factor 5A, eIF5AI, EIF-5A

EIF5A Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.9 kDa and the accession number is P63241-1.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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EIF5A Protein, Human, Recombinant (His)

规格	价格/CNY		货期	数量
100 μg	￥ 4,460		5日内发货

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参考文献

生物活性	Testing in progress
产品描述	EIF5A Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.9 kDa and the accession number is P63241-1.

种属	Human
表达系统	E. coli
标签	N-His
蛋白编号	P63241-1
别名	EIF5A1, eukaryotic translation initiation factor 5A, eIF5AI, EIF-5A
蛋白构建	Human EIF5A (NP_001961.1) (Met1-Lys154)
蛋白纯度	> 85 % as determined by SDS-PAGE
分子量	18.9 kDa (predicted)

内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiation complex. In protein synthesis initiation, eIF2 functions in its GTP-bound state to deliver initiator methionyl-tRNA to the small ribosomal subunit and is necessary for protein synthesis in all cells. EIF-5A stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI). EIF-5A also interacts with eIF1 and eIF3 and binds the eIF2-GTP/Met-tRNA ternary complex along with the 40S ribosome subunit.

参考文献

1. Jenkins ZA. et al., 2001, Genomics. 71 (1): 101-9. 2. Guan XY. et al., 2001, Cancer Res. 61 (9): 3806-9. 3. Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903. 4. Clement PM. et al., 2003, Eur J Biochem. 270 (21): 4254-63.

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Keywords

EIF5A Protein, Human, Recombinant (His) EIF5A1 eukaryotic translation initiation factor 5A eIF5AI EIF-5A recombinant recombinant-proteins proteins protein

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