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PSMB8 Protein, Human, Recombinant (His & Myc & SUMO)

产品编号 TMPH-01928

别名: Proteasome subunit beta type-8, Proteasome component C13, Really interesting new gene 10 protein, Macropain subunit C13, Low molecular mass protein 7, PSMB8, Multicatalytic endopeptidase complex subunit C13, Proteasome subunit beta-5i

PSMB8 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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PSMB8 Protein, Human, Recombinant (His & Myc & SUMO)

规格	价格/CNY		货期	数量
20 μg	￥ 1,320		20日内发货
100 μg	￥ 2,470		20日内发货
1 mg	￥ 10,700		20日内发货

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产品性质

产品描述	PSMB8 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.

种属	Human
表达系统	E. coli
标签	N-10xHis-SUMO, C-Myc
蛋白编号	P28062
别名	Proteasome subunit beta type-8, Proteasome component C13, Really interesting new gene 10 protein, Macropain subunit C13, Low molecular mass protein 7, PSMB8, Multicatalytic endopeptidase complex subunit C13, Proteasome subunit beta-5i
氨基酸序列	TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
蛋白构建	73-276 aa
蛋白纯度	> 85% as determined by SDS-PAGE.
分子量	42.7 kDa (predicted)

缓冲液	Tris-based buffer, 50% glycerol
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Involved in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.

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Keywords

PSMB8 Protein, Human, Recombinant (His & Myc & SUMO) Proteasome subunit beta type-8 Proteasome component C13 Really interesting new gene 10 protein Macropain subunit C13 Low molecular mass protein 7 PSMB8 Multicatalytic endopeptidase complex subunit C13 Proteasome subunit beta-5i recombinant recombinant-proteins proteins protein

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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