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GABRB2 Protein, Human, Recombinant (His)

GABRB2 Protein, Human, Recombinant (His)

产品编号 TMPH-01367
别名: GABA(A) receptor subunit beta-2, GABRB2, Gamma-aminobutyric acid receptor subunit beta-2

GABRB2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.3 kDa and the accession number is P47870.

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GABRB2 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,800 20日内发货
100 μg ¥ 3,420 20日内发货
1 mg ¥ 14,600 20日内发货
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产品目录号及名称: GABRB2 Protein, Human, Recombinant (His) (TMPH-01367)
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产品描述 GABRB2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.3 kDa and the accession number is P47870.
种属 Human
表达系统 E. coli
标签 N-6xHis
蛋白编号 P47870
别名 GABA(A) receptor subunit beta-2, GABRB2, Gamma-aminobutyric acid receptor subunit beta-2
氨基酸序列 SVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGY
蛋白构建 26-244 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 29.3 kDa (predicted)
缓冲液 If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法 Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity. Functions also as histamine receptor and mediates cellular responses to histamine.

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Keywords

GABRB2 Protein, Human, Recombinant (His) GABA(A) receptor subunit beta-2 GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 recombinant recombinant-proteins proteins protein

 

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