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yGsy2p-IN-H23
还可以产品编号 T38674Cas号 1269190-98-8
别名 yGsy2p-IN-H23
yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds precisely within the uridine diphosphate glucose (UDPG) binding pocket of yGsy2p. Its utilization in research primarily focuses on studying glycogen storage diseases (GSDs).
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yGsy2p-IN-H23
还可以产品编号 T38674 别名 yGsy2p-IN-H23Cas号 1269190-98-8
yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds precisely within the uridine diphosphate glucose (UDPG) binding pocket of yGsy2p. Its utilization in research primarily focuses on studying glycogen storage diseases (GSDs).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 984 | 5日内发货 | |
| 5 mg | ¥ 1,660 | 5日内发货 | |
| 25 mg | ¥ 6,190 | 6-8周 | |
| 50 mg | ¥ 7,890 | 6-8周 | |
| 100 mg | ¥ 11,200 | 6-8周 | |
| 1 mL x 10 mM (in DMSO) | ¥ 1,830 | 5日内发货 |
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生物活性
化学信息
| 产品描述 | yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds precisely within the uridine diphosphate glucose (UDPG) binding pocket of yGsy2p. Its utilization in research primarily focuses on studying glycogen storage diseases (GSDs). |
| 靶点活性 | GYS1 (human):875 µM (IC50) |
| 体外活性 | yGsy2p-IN-H23 (compound H23) has IC 50 values against either hGYS1Δ634S8,11N or wild-type hGYS1 were 161 μM and 875 μM, respectively. yGsy2p-IN-H23 exhibits IC 50 values of 280 μM and 263 μM in the absence and presence of G6P for yGsy2p against yeast and human glycogen synthase (GS), respectively. yGsy2p-IN-H23 is not in direct competition with G6P[1]. |
| 别名 | yGsy2p-IN-H23 |
| 分子量 | 377.488 |
| 分子式 | C23H27N3O2 |
| CAS No. | 1269190-98-8 |
| 密度 | 1.19 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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