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Search Results for " antagonist "

Targets Recommended: Estrogen/progestogen Receptor

4846

抑制剂 & 化合物

133

天然产物

3

化合物库

35

重组蛋白

105

同位素标记化合物

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Cat. No.	Product Name
L7200	钙通道分子库		140 compounds
	140 种钙通道相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；
L9830	抗帕金森病化合物库		857 compounds
	857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

钙通道分子库

Cat.No: L7200

Compounds: 140

抗高血压化合物库

Cat.No: L7110

Compounds: 678

抗帕金森病化合物库

Cat.No: L9830

Compounds: 857

Cat. No.	Product Name	Target	Signaling Pathways
T11230	ERRα antagonist-1 ERR+/- antagonist-1,ERRa antagonist-1	Estrogen/progestogen Receptor	Endocrinology/Hormones
	ERRα antagonist-1 (ERR+/- antagonist-1) 是一种选择性的，高亲和力的雌激素相关受体α (ERRα) 拮抗剂。ERRα antagonist-1 抑制 ERRα 与增殖物激活的受体γ共激活因子 1α (PGC-1α) 和 PGC-1β 的相互作用，IC50 值分别为 170 nM 和 180 nM。ERRα antagonist-1 不抑制 ERRβ 或 ERRγ 与 PGC-1α 和 PGC-1β 共激活剂的相互作用，也不抑制 ERα 或 ERβ 与 PGC-1α 或 SRC-1 的相互作用。
T39078	CXCR7 antagonist-1 CXCR7 antagonist-1	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	CXCR7 antagonist-1 是 SDF-1 趋化因子或 I-TAC 与趋化因子受体 CXCR7 结合的特异性拮抗剂。 CXCR7 antagonist-1 可防止肿瘤细胞增殖和肿瘤形成，可用于炎症性疾病的研究。
T37793	A2B receptor antagonist 2 A2B receptor antagonist 2	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2B receptor antagonist 2 是腺苷受体 A2B 的拮抗剂（rA1 的 Ki = 2.30 μM，rA2A 的 Ki = 6.8 μM，hA2B 的 3.44 μM）。
T10031	EP1-antagonist-1 EP1-antanoist-1,EP1 antagonist 1	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	EP1-antagonist-1 (EP1 antagonist 1) 是 EP1 的拮抗剂，pKi 和 pIC50 分别为 7.54 和 8.5。
T15785	LPA1 receptor antagonist 1 LPA1 R antagonist 1	LPA Receptor	GPCR/G Protein
	LPA1 receptor antagonist 1(LPA1 R antagonist 1) 是一种具有选择性和高效性的溶血磷脂酸 (LPA1) 受体拮抗剂( IC50 : 25 nM)，可用于研究特发性肺纤维化。
T37792	A2A receptor antagonist 1 CPI-444 analog,A2A receptor antagonist 1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2A receptor antagonist 1 (CPI-444 analog)是腺苷 A2A 和 A1受体的拮抗剂，Ki 值分别为4和264 nM。
T10250	ADRA1D receptor antagonist 1 HCl ADRA1D receptor antagonist 1 HCl（1191908-24-3 free base）	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	ADRA1D receptor antagonist 1 HCl 是一种具有口服活性、高效性和选择性的 α1D 肾上腺素受体拮抗剂（Ki：1.6 nM），具有潜在的抗增殖活性。
T13216	TSHR antagonist S37	TSH Receptor	GPCR/G Protein
	TSHR antagonist S37 是促甲状腺激素受体 (TSHR) 的选择性和竞争性拮抗剂。
T9709	TRPM8 antagonist 3	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM8 antagonist 3 是 TRPM8 的阻断剂 (IC50 = 11 nM)。
T10712	CCR2 antagonist 3 AZD-2927,AZD2927	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2 antagonist 3 (AZD-2927) 是 CCR2的拮抗剂。
T5698	TRPM8 antagonist 2	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM8 antagonist 2 是有效的 RPM8选择性 T 拮抗剂，IC50值为 0.2 nM，在神经性疼痛综合症中有研究价值。
T9983	CCR8 antagonist 1 LUN04765	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR8 antagonist 1 是 C-C Motif 趋化因子受体 8 (CCR8) 的拮抗剂，Ki 值为 1.6 nM。
T10708	CCR1 antagonist 6	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR1 antagonist 6是一种 CCR1 拮抗剂（IC50 ：3 nM）。
TP1935L1	RAGE antagonist peptide acetate	Beta Amyloid	Neuroscience
	RAGE antagonist peptide acetate 是一种高级的糖基化终产物 (RAGE) 拮抗剂。它具有抗肿瘤和抗炎活性。它可防止 RAGE 与其几个重要的配体结合，包括 HMGB-1、S100P 和 S100A4。
T5622	BAY-218 AHR antagonist 1	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	BAY-218 (AHR antagonist 1) 是一种芳基烃受体(AHR)拮抗剂，在人细胞系中的IC50值为 39.9 nM。
T10084	CRTh2 antagonist 1	GPR	Endocrinology/Hormones; GPCR/G Protein
	CRTh2 antagonist 1 是 CRTh2 拮抗剂，IC50 值为 89 nM。
T10156	CCR3 antagonist 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR3 antagonist 1是一种有效的 CCR3拮抗药，用于炎症和免疫疾病的研究。
T8848	GPR34 receptor antagonist 2 Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-,gpr34-receptor-antagonist-2	Others	Others
	GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) 是一种GPR34受体拮抗剂，可用于研究免疫疾病、炎性疾病。
T5829	H4 Receptor antagonist 1	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	H4 Receptor antagonist 1 是选择性组胺 H4受体反向激动剂，其IC50值为19 nM。
T11966	MCHR1 antagonist 2	HER; Melanin-concentrating Hormone Receptor (MCHR)	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	MCHR1 antagonist 2 是有效的黑色素聚集激素受体 1 拮抗剂，IC50为 65 nM。它也抑制hERG，在IMR-32 细胞中的IC50为 4.0 nM。
T10169	5-HT4 antagonist 1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT4 antagonist 1 是 5-HT4 的拮抗剂 (pKi = 9.6)。
T13435	TR antagonist 1	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	TR antagonist 1 是一种高效甲状腺激素受体（TR）拮抗剂（对 TRα 和 TRβ 的 IC50 分别为 36 和 22 nM），可用于研究内分泌异常引起的疾病。
T37429	TRPV3 antagonist 74a TRPV3 74a	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPV3 antagonist 74a (TRPV3 74a) 是一种特异性 TRPV3 拮抗剂，可用于研究神经系统相关疾病。
T10359	AR antagonist 1	Androgen Receptor; Ligand for E3 Ligase; Ligands for Target Protein for PROTAC	Endocrinology/Hormones; PROTAC
	AR antagonist 1 是 AR 拮抗剂，能够与 E3 连接酶配体结合，与 VHL 蛋白结合亲和力较弱，用于 PROTACARD-266 合成。
T14881	CB1 antagonist 2 AM4113	Cannabinoid Receptor	GPCR/G Protein
	CB1 antagonist 2 (AM4113) 是一种 caimabinoid 1 拮抗剂，在体内抑制 CB1 的IC50值为 25.5 nM。
T12320	ORL1 antagonist 1	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	ORL1 antagonist 1是阿片样受体1 (ORL1) 拮抗剂， IC50 值为 61 nM。
T10889	CRTh2 antagonist 2	GPR	Endocrinology/Hormones; GPCR/G Protein
	CRTh2 antagonist 2 是一种有效的选择性 CRTH2 抑制剂，对 CRTH2 的 IC50 值为 ≤10 nM。CRTh2 antagonist 2 可用于雄激素性脱发的研究。
T10058	A2B receptor antagonist 1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2B receptor antagonist 1 是一个有效的 A2B 腺苷受体 (A2B adenosine receptor) 拮抗剂。
T12910	Sigma-1 receptor antagonist 1	Sigma receptor	GPCR/G Protein
	Sigma-1 receptor antagonist 1 是一种有效、特异性的 sigma-1 受体拮抗剂。 Sigma-1 receptor antagonist 1 具有抗神经性疼痛活性，可用于治疗神经性疼痛研究。
T11211	EP4 receptor antagonist 1	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	EP4 receptor antagonist 1 是一种有效的特异性前列腺素 EP4受体拮抗剂，对人和小鼠 EP4受体的 IC50分别为6.1 nM 和16.2 nM。 EP4 receptor antagonist 1 可用于癌症免疫治疗的研究。
T10269	AHR antagonist 2	Aryl Hydrocarbon Receptor	Immunology/Inflammation
	AHR antagonist 2 是芳基烃受体的拮抗剂。人 AHR 和小鼠 AHR 的 IC50 分别为 0.885 和 2.03 nM。
T13453	CGRP antagonist 1	CGRP Receptor	GPCR/G Protein; Neuroscience
	CGRP antagonist 1是高效 CGRP 受体拮抗剂，Ki 值分别为 35nM，IC50 值为 57 nM。CGRP antagonist 1可用于研究心血管疾病和神经血管疾病。
T5522	NMDAR antagonist 1	Others; iGluR	Membrane transporter/Ion channel; Neuroscience; Others
	NMDAR antagonist 1 是一种 NR2B 选择性的、口服具有活力的 NMDAR 拮抗剂。
T12911	Sigma-1 receptor antagonist 2	Sigma receptor	GPCR/G Protein
	Sigma-1 receptor antagonist 2 是有效的sigma 1受体选择性拮抗剂，与 σ1 和 σ2 受体结合的Ki 分别为 3.88 和 1288 nM。
T39762	AHR antagonist 5 free base	Aryl Hydrocarbon Receptor	Immunology/Inflammation
	AHR antagonist 5 free base 是一种具有口服活性的 AHR 拮抗剂，在人和啮齿动物细胞系中的 IC50 约为 35-150 nM。
T11635	IL-17A antagonist 1	IL Receptor	Immunology/Inflammation
	IL-17A antagonist 1 是一种 IL-17A 拮抗剂，可用于研究和白介素相关的炎症和免疫疾病。
T10162	5-HT3 antagonist 3	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT3 antagonist 3 是一种高亲和力的 5-HT3 受体拮抗剂。5-HT3 antagonist 3 结合到大鼠脑皮质膜中的 5-HT3 受体，Ki 为 0.25 nM。
T10248	Adenosine antagonist-1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Adenosine antagonist-1 可作为一种腺苷 A3 受体 (AA3R) 拮抗剂。
T12912	Sigma-1 receptor antagonist 3	Sigma receptor; HER	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Sigma-1 receptor antagonist 3 是 Sigma-1受体选择性拮抗剂，Ki 为 1.14 nM。它抑制 hERG，IC50为 1.54μM。它在神经性疼痛方面有研究的价值。
T12597	5-HT2 antagonist 1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2 antagonist 1 是一种有效的 5-HT2 receptor 拮抗剂，同时对 α1 adrenoceptor 有微弱地抑制作用。
T9244	σ1 Receptor antagonist-1	Sigma receptor	GPCR/G Protein
	σ1 Receptor antagonist-1 是高选择性的 sigma 1受体拮抗剂，pKi 为10.28。它抑制细胞生长，在 G0/G1 期阻滞细胞周期并诱导 MCF-7/ADR 细胞凋亡。
T11851	Lin28-let-7a antagonist 1	Others	Others
	Lin28-let-7a antagonist 1 对 Lin28A-let-7a-1 相互作用的 IC50 为 4.03 μM，对 Lin28-let-7a 相互作用有明显的拮抗作用。
T13114	CCR2 antagonist 4 Teijin compound 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂，对 CCR2b 的IC50为 180 nM，抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。
T9846	5-HT3 antagonist 5	Others	Others
	5-HT3 antagonist 5 是喹喔啉 -2- 甲酰胺化合物，是一种5-HT3受体拮抗剂。5-HT3 antagonist 5 对5-HT3激动剂和2-甲基-5-HT 也具有拮抗作用，并在小鼠中表现出抗抑郁作用。
T38622	Bcl-xL antagonist 2	BCL	Apoptosis
	Bcl-xL antagonist 2 是一种有效的选择性 Bcl-xL 拮抗剂，IC50 为 91 nM，Ki 为 65 nM。 Bcl-xL antagonist 2 可诱导癌细胞凋亡，可用于慢性淋巴细胞白血病和非霍奇金淋巴瘤的研究。
T9723	GluR6 antagonist-1	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	GluR6 antagonist-1 抑制酪氨酸激酶 p56lck SH2 结构域的 pY 结合位点。
T11560	hGPR91 antagonist 1 (S)-2-(4-(1,8-萘啶-2-基)苯基)-N-(1-(4'-氟-3'-(三氟甲基)-[1,1'-联苯]-4-基)乙基)乙酰胺	GHSR	GPCR/G Protein
	HGPR91 antagonist 1 是小分子hGPR91选择性拮抗剂(IC50:7 μM)。
T60145	CCR6 antagonist 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR6 antagonist 1 是一种 CCR6 拮抗剂，可抑制 CCL20/CCR6 信号通路。 CCR6 antagonist 1 可用于自身免疫介导的炎症性疾病的研究，如炎症性肠病 (IBDs)。
T27682	CCR2 antagonist 5 JNJ-41443532,JNJ-41443532 Free Base,JNJ 41443532,JNJ41443532	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2 antagonist 5 (JNJ-41443532) 是一种具有选择性和口服活性的 hCCR2 抑制剂，具有良好的结合亲和力 (IC50=37 nM) 和有效的功能拮抗作用 (chemotaxis IC50=30 nM)。JNJ-41443532 对 mCCR2 结合的 Ki 为 9.6 µM，可用于研究炎症性疾病和糖尿病。
T15387	GLP-1R Antagonist 1	Glucagon Receptor	GPCR/G Protein
	GLP-1R Antagonist 1 (compound 5d) 是口服有效的、能透过中枢神经系统的，胰高血糖素样肽 1 受体 (GLP-1R) 的非竞争性抑制，其 IC50 值为 650 nM。

化合物

ERRα antagonist-1

Cat.No: T11230

Synonym: ERR+/- antagonist-1,ERRa antagonist-1

Target: Estrogen/progestogen Receptor

CXCR7 antagonist-1

Cat.No: T39078

Synonym: CXCR7 antagonist-1

Target: CXCR

A2B receptor antagonist 2

Cat.No: T37793

Synonym: A2B receptor antagonist 2

Target: Adenosine Receptor

EP1-antagonist-1

Cat.No: T10031

Synonym: EP1-antanoist-1,EP1 antagonist 1

Target: Prostaglandin Receptor

LPA1 receptor antagonist 1

Cat.No: T15785

Synonym: LPA1 R antagonist 1

Target: LPA Receptor

A2A receptor antagonist 1

Cat.No: T37792

Synonym: CPI-444 analog,A2A receptor antagonist 1

Target: Adenosine Receptor

ADRA1D receptor antagonist 1 HCl

Cat.No: T10250

Synonym: ADRA1D receptor antagonist 1 HCl（1191908-24-3 free base）

Target: Adrenergic Receptor

TSHR antagonist S37

Cat.No: T13216

Target: TSH Receptor

TRPM8 antagonist 3

Cat.No: T9709

Target: TRP/TRPV Channel

CCR2 antagonist 3

Cat.No: T10712

Synonym: AZD-2927,AZD2927

Target: CCR

TRPM8 antagonist 2

Cat.No: T5698

Target: TRP/TRPV Channel

CCR8 antagonist 1

Cat.No: T9983

Synonym: LUN04765

Target: CCR

CCR1 antagonist 6

Cat.No: T10708

Target: CCR

RAGE antagonist peptide acetate

Cat.No: TP1935L1

Target: Beta Amyloid

Cat.No: T5622

Synonym: AHR antagonist 1

Target: AhR, Aryl Hydrocarbon Receptor

CRTh2 antagonist 1

Cat.No: T10084

Target: GPR

CCR3 antagonist 1

Cat.No: T10156

Target: CCR

GPR34 receptor antagonist 2

Cat.No: T8848

Synonym: Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-,gpr34-receptor-antagonist-2

Target: Others

H4 Receptor antagonist 1

Cat.No: T5829

Target: Histamine Receptor

MCHR1 antagonist 2

Cat.No: T11966

Target: HER, Melanin-concentrating Hormone Receptor (MCHR)

5-HT4 antagonist 1

Cat.No: T10169

Target: 5-HT Receptor

TR antagonist 1

Cat.No: T13435

Target: Thyroid hormone receptor(THR)

TRPV3 antagonist 74a

Cat.No: T37429

Synonym: TRPV3 74a

Target: TRP/TRPV Channel

AR antagonist 1

Cat.No: T10359

Target: Androgen Receptor, Ligand for E3 Ligase, Ligands for Target Protein for PROTAC

CB1 antagonist 2

Cat.No: T14881

Synonym: AM4113

Target: Cannabinoid Receptor

ORL1 antagonist 1

Cat.No: T12320

Target: Opioid Receptor

CRTh2 antagonist 2

Cat.No: T10889

Target: GPR

A2B receptor antagonist 1

Cat.No: T10058

Target: Adenosine Receptor

Sigma-1 receptor antagonist 1

Cat.No: T12910

Target: Sigma receptor

EP4 receptor antagonist 1

Cat.No: T11211

Target: Prostaglandin Receptor

AHR antagonist 2

Cat.No: T10269

Target: Aryl Hydrocarbon Receptor

CGRP antagonist 1

Cat.No: T13453

Target: CGRP Receptor

NMDAR antagonist 1

Cat.No: T5522

Target: Others, iGluR

Sigma-1 receptor antagonist 2

Cat.No: T12911

Target: Sigma receptor

AHR antagonist 5 free base

Cat.No: T39762

Target: Aryl Hydrocarbon Receptor

IL-17A antagonist 1

Cat.No: T11635

Target: IL Receptor

5-HT3 antagonist 3

Cat.No: T10162

Target: 5-HT Receptor

Adenosine antagonist-1

Cat.No: T10248

Target: Adenosine Receptor

Sigma-1 receptor antagonist 3

Cat.No: T12912

Target: Sigma receptor, HER

5-HT2 antagonist 1

Cat.No: T12597

Target: 5-HT Receptor

σ1 Receptor antagonist-1

Cat.No: T9244

Target: Sigma receptor

Lin28-let-7a antagonist 1

Cat.No: T11851

Target: Others

CCR2 antagonist 4

Cat.No: T13114

Synonym: Teijin compound 1

Target: CCR

5-HT3 antagonist 5

Cat.No: T9846

Target: Others

Bcl-xL antagonist 2

Cat.No: T38622

Target: BCL

GluR6 antagonist-1

Cat.No: T9723

Target: Src

hGPR91 antagonist 1

Cat.No: T11560

Synonym: (S)-2-(4-(1,8-萘啶-2-基)苯基)-N-(1-(4'-氟-3'-(三氟甲基)-[1,1'-联苯]-4-基)乙基)乙酰胺

Target: GHSR

CCR6 antagonist 1

Cat.No: T60145

Target: CCR

CCR2 antagonist 5

Cat.No: T27682

Synonym: JNJ-41443532,JNJ-41443532 Free Base,JNJ 41443532,JNJ41443532

Target: CCR

GLP-1R Antagonist 1

Cat.No: T15387

Target: Glucagon Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T21615	Guanidinoethyl sulfonate 脒基牛磺酸,Taurocyamine	Chloride channel	Membrane transporter/Ion channel
	Guanidinoethyl sulfonate (Taurocyamine) 它是一种牛磺酸的结构类似物，也是牛磺酸转运的竞争性拮抗剂。它能够诱导怀孕大鼠排泄含有大量牛磺酸的尿液，导致组织中牛磺酸含量降低，从而容易产生牛磺酸缺乏的胎鼠。
T8268	6,2'-Dihydroxyflavone 6,2-二羟基黄酮,6,2'-二羟基黄酮	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	6,2'-Dihydroxyflavone 是一种新型GABAA 受体拮抗剂。
T21499	Dimebolin Latrepirdine,Dimebon,Dimebone	5-HT Receptor	GPCR/G Protein; Neuroscience
	Dimebolin (Latrepirdine) 是一种 5-HT6 拮抗剂。
T3917	Protopanaxatriol 20(R)-APPT,20(R)-Protopanaxatriol,原人参三醇,(20R)-Protopanaxatriol	PPAR	DNA Damage/DNA Repair; Metabolism
	Protopanaxatriol (20(R)-APPT) 是天然的人参皂苷的糖苷配基，包括 Re，Rf，Rg1，Rg2 和 Rh。
TN1519L	(-)-Coclaurine hydrochloride (-)-Coclaurine hydrochloride (486-39-5 Free base)	AChR	Neuroscience
	(-)-Coclaurine hydrochloride 是从 Sarcopetalum harveyanum 中分离出来的，是一种 nAChR 拮抗剂。
TQ0197	Acenocoumarol 醋硝香豆素,新抗凝
	Acenocoumarol 是一种抗凝血剂，与 Vitamin K 拮抗剂的功能相似。
T19713	HHQ 2-庚基-4-喹啉酮,2-heptylquinolin-4(1H)-one	Others	Others
	HHQ (2-heptylquinolin-4(1H)-one) 是一种 PqsR 拮抗剂。
T3S2100	(-)-Securinine 一叶秋碱,Securinine	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	(-)-Securinine (Securinine) 是来自叶底珠的一种生物碱，也是 GABAA 受体拮抗剂。
TJS0341	7-Amino-4-(trifluoromethyl)coumarin 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素	5-HT Receptor	GPCR/G Protein; Neuroscience
	7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物，其激发和发射波长分别为400和500 nm，可用来灵敏的检测蛋白酶。
T7177	Capsazepine	Apoptosis; TRP/TRPV Channel	Apoptosis; Membrane transporter/Ion channel
	Capsazepine 是一种 TRPV1 受体的拮抗剂， IC50值为 562 nM。它可阻断由激活 TRPV1 离子通道的辣椒素引起的热痛感，是辣椒素拮抗剂。
T2751	Ginkgolide B BN-52021,银杏内酯B	Apoptosis; PAFR; Endogenous Metabolite	Apoptosis; GPCR/G Protein; Metabolism
	Ginkgolide B (BN-52021) 是一种萜类物质，是银杏叶中的重要的活性物质之一。
T21504	γ-Linolenic Acid methyl ester Methyl gamma-linolenate,γ-亚麻酸甲酯	LTR	Immunology/Inflammation
	γ-Linolenic Acid methyl ester (Methyl gamma-linolenate) 是一种弱白三烯 B4 (LTB4) 受体拮抗剂。
T8304	Anisodamine Hydrobromide 6-Hydroxyhyoscyamine,氢溴酸山莨菪碱	Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) 是来自颠茄的一种生物碱，具有抗氧化、抗炎活性。它也是一种非亚型的选择性毒蕈碱和烟碱类胆碱受体拮抗剂。
T0525	Flopropione 夫洛丙酮,Phloropropiophenone	5-HT Receptor; Transferase	GPCR/G Protein; Metabolism; Neuroscience
	Flopropione (Phloropropiophenone) 是一种解痉剂，用作 5-HT1A 受体拮抗剂，也是儿茶酚-O-甲基转移酶抑制剂。
T0354	Canrenone 6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,坎利酮,RP-11614,SC14266	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Canrenone (SC14266) 是一种醛固酮 (aldosterone) 拮抗剂，广泛用作利尿剂。
TN1465	Cannabigerol	NOS; 5-HT Receptor; ROS	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cannabigerol 是一种植物大麻素，是一种高亲和力 α2-肾上腺素能受体激动剂、中度亲和力 5-HT1A 受体拮抗剂和低亲和力 CB1/CB2受体拮抗剂。它可降低眼压，有潜力治疗青光眼。
T3668	Galangin Norizalpinin,高良姜素,3,5,7-Trihydroxyflavone	ERK; P450; NF-κB; Autophagy	Autophagy; MAPK; Metabolism; NF-κB
	Galangin (Norizalpinin) 是芳烃受体的激动剂/拮抗剂，并且还显示对 CYP1A1 活性的抑制作用。
T1680	Tolazoline hydrochloride Imidaline hydrochloride,苯甲唑啉盐酸盐,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Tolazoline hydrochloride (NSC35110(hydrochloride)) 是一种 α 肾上腺素受体抑制剂。
T3379	Decanoic Acid Decoic acid,CAPRIC ACID,Caprynic acid,癸酸	GluR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Decanoic Acid (Caprynic acid) 是中链甘油三酯中的成分，是非竞争性和可透过血脑屏障的 AMPA 受体抑制剂，具有抗癫痫作用。
T0970	Racanisodamine 山莨菪碱,Anisodamine,7β-Hydroxyhyoscyamine,Raceanisodamine,消旋山莨菪碱	Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Racanisodamine (7β-Hydroxyhyoscyamine) 是 anisodamine 的消旋体，是非选择性的毒蕈碱拮抗剂，是近视控制滴眼液的有效成分。
T5743	Gymnemagenin	Liver X Receptor	Metabolism
	Gymnemagenin 是一种分离自G. sylvestre 的三萜。它具有抗病毒作用，对糖尿病和肥胖症具有潜在的研究价值。
T2S1464	Thiocolchicoside 硫秋水仙苷;噻可撒可,Thiocolchicine 2-glucoside analog,硫秋水仙苷,Coltramyl	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	Thiocolchicoside (Thiocolchicine 2-glucoside analog) 是秋水仙碱的半合成硫衍生物，是竞争性 GABAA 受体拮抗剂和甘氨酸受体拮抗剂。它是肌肉松弛剂，具有抗炎作用，可用于缓解疼痛的研究。
T20884	Hydroxyzine Hydroxyzine free base,羟嗪	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Hydroxyzine (Hydroxyzine free base) 是一种组胺 H1 受体拮抗剂，可有效治疗慢性荨麻疹、皮炎和组胺介导的瘙痒。它可作为止吐剂和镇静剂，缓解焦虑和紧张。
T1156	Palonosetron hydrochloride 盐酸帕洛诺司琼,RS 25259 197,Palonosetron HCl,RS 25259	5-HT Receptor	GPCR/G Protein; Neuroscience
	Palonosetron hydrochloride (RS 25259) 是一种 5-HT3 拮抗剂，用于预防和治疗化疗引起的恶心和呕吐。
TQ0027	Transcrocetinate disodium Disodium trans-crocetinate,藏红花,藏红花酸二钠盐	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Transcrocetinate disodium (Disodium trans-crocetinate) 从藏红花中提取的一种天然产物，是高亲和力NMDA 受体拮抗剂。
T1186	Ifenprodil Tartrate	Potassium Channel; NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Ifenprodil tartrate 是典型的非竞争性 NMDA 受体拮抗剂，抑制 GIRK (Kir3)，通过基底 GIRK 活性减少内向电流，有用做脑血管舒张试剂的潜力。它对 NR1A/NR2B 受体亲和力是 NR1A/NR2A 受体的 400 倍。
T0268	Lobeline hydrochloride 盐酸洛贝林,α-Lobeline hydrochloride,L-Lobeline hydrochloride	AChR	Neuroscience
	Lobeline hydrochloride (α-Lobeline hydrochloride) 是一种烟碱样受体激动剂，是神经元烟碱受体α3β2和α4β2拮抗剂。
T2815	Puerarin 葛根素,Kakonein	5-HT Receptor	GPCR/G Protein; Neuroscience
	Puerarin (Kakonein) 是从葛根中提取的一种异黄酮，是一种5-HT2C 受体拮抗剂。
T4429	Rauwolscine hydrochloride Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂，Ki=12 nM。
T21165	Pellitorine AI3-19560,墙草碱,Pellitorin	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pellitorine (Pellitorin) 是提取自 Piper nigrum 的根的一种化合物。它对 HL60 和 MCT-7 细胞系表现出显著的细胞毒活性。它可用于癌症疾病的研究。
T16535	Picrotoxinin	Chloride channel; GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Picrotoxinin 是一种氯离子通道阻断剂和 GABAA 的非竞争性拮抗剂，对 α1β2γ2L GABAA 的 IC50 为 1.15 μM。 Picrotoxinin 具有惊厥作用。
T7939	Fingolimod 2-氨基-2-[2-(4-辛基苯基)乙基]-1,3-丙二醇,FTY-720A,FTY-720,芬戈莫德	S1P Receptor; PAK; LPL Receptor	Cytoskeletal Signaling; GPCR/G Protein
	Fingolimod (FTY-720A) 是一种 1-磷酸鞘氨醇 (S1P) 拮抗剂，作用于 K562 和 NK 细胞，IC50为 0.033 nM。它还是pak1激活剂和免疫抑制剂。
T2898	Andrographolide Andrographis,穿心莲内酯	SARS-CoV; Influenza Virus; NF-κB; Autophagy	Autophagy; Microbiology/Virology; NF-κB
	Andrographolide (Andrographis) 是 NF-κB 的不可逆拮抗剂，具有抗病毒、抗炎和抗血小板聚集活性和潜在的抗肿瘤作用。
T21581L	AC 187 Acetate AC 187 Acetate (151804-77-2 Free base)	Amylin Receptor	GPCR/G Protein
	AC 187 Acetate 是胰淀素受体的强效拮抗剂。AC 187 对胰淀素受体的选择性高于降钙素和 CGRP 受体。
T2825	Cyclopamine 环巴胺,11-Deoxojervine	Hedgehog/Smoothened; Endogenous Metabolite; Smo	GPCR/G Protein; Metabolism; Stem Cells
	Cyclopamine (11-Deoxojervine) 是Hedgehog 通路的拮抗剂，细胞实验中IC50=46 nM。它还是选择性Smo 抑制剂。
T3915	Ginsenoside Ro 人参皂苷Ro,Chikusetsusaponin 5,Polysciasaponin P3,人参皂苷 Ro,Chikusetsusaponin V	Calcium Channel; Reductase; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
	Ginsenoside Ro (Chikusetsusaponin V) 能降低 TXA2产量，较弱降低 COX-1 和 TXAS 活性，具有 Ca2+拮抗剂的抗血小板作用，IC50为 155 μM。
T10822	Cirsimarin Cirsitakaoside	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Cirsimarin (Cirsitakaoside) 是一种从 Microtea debilis 中分离出来的黄酮类化合物。它具有很强的抗脂肪生成作用，能减少小鼠脂肪组织的沉积。Cirsimarin 对腺苷 A1 受体有拮抗作用，对磷酸二酯酶有抑制作用
TN1849	Kuwanon H	GPR; Bombesin Receptor	Endocrinology/Hormones; GPCR/G Protein
	Kuwanon H 是分离自桑白皮的黄酮类化合物，具有拮抗非肽类蛙皮素受体的活性。Kuwanon H 特异性抑制细胞内胃泌激素释放肽 CRP 与GRP-preferring 受体的结合，Ki 为 290 nM。
T22583	Arcaine sulfate	NMDAR	Neuroscience
	Arcaine sulfate 是一种多胺，是 N-甲基-d-天冬氨酸 (NMDA) 受体多胺结合位点的拮抗剂。 Arcaine 是一种胍丁胺类似物，与 ifenprodil 一起，可能有可能用于治疗癫痫疾病。
T7060	Amantadine 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine	Others	Others
	Amantadine (1-Aminoadamantane) 是抗病毒药物，也是是 NMDA 型谷氨酸受体的弱拮抗剂，能促进高多巴胺的释放，并阻断多巴胺的再摄取。
T3865	beta-Eudesmol β-桉叶醇,Beta-Selinenol,beta-桉叶醇	TRP/TRPV Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	beta-Eudesmol (Beta-Selinenol) 是天然的含氧倍半萜烯，可激活hTRPA1，EC50值为 32.5 μM。Beta-Eudesmol 有增加食欲的功效。
T6648	Rotundine Gindarine,L-Tetrahydropalmatine,Caseanine,罗通定,(-)-Tetrahydropalmatine	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Rotundine (Gindarine) 是多巴胺D1、D2和D3受体的拮抗剂，IC50值分别为 166、1.4 和 3.3 μM。它也是5-HT1A 的拮抗剂，IC50值为 370 nM。
T5776	pimpinellin	Apoptosis; Anti-infection	Apoptosis; Microbiology/Virology
	Pimpinellin 是贯众的一种成分，可通过诱导肿瘤细胞凋亡抑制肿瘤细胞的生长，可作为具有 GABA 受体活性的蛋白质的拮抗剂。
T6S0109	Sipeimine Kashmirine,西贝母碱,Imperialine,西贝碱	Others	Others
	Sipeimine (Kashmirine) 是一种天然产物，从平贝母中分离得到。
TN2247	Swertisin	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Swertisin 是从日本紫菜中分离出的 C-葡萄糖基黄酮，是腺苷 A1 受体拮抗剂，具有抗糖尿病、抗炎和抗氧化作用。
TN7129	Methyl maslinate 马斯里酸甲酯,Maslinic acid methyl ester,Crategolic acid methyl ester	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Methyl maslinate (Maslinic acid methyl ester) 是一种具有强心和抗心律失常特性的 β-肾上腺素受体拮抗剂。Methyl maslinate 可用于高血压研究。
T5S0273	Hypaphorine Lenticin,Glyyunnanenine,Tryptophan Betaine,刺桐碱	Others	Others
	Hypaphorine (Lenticin) 是一种提取自 Pisolithus tinctorius 中的吲哚类生物碱，对啮齿动物具有有神经学影响降糖活性。
T8373	6-Diazo-5-oxo-L-nor-Leucine DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine	Influenza Virus; Glutaminase; Antibacterial; Antibiotic	Microbiology/Virology; Proteases/Proteasome
	6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) 是一种谷氨酰胺拮抗剂，具有抗菌、抗病毒和抗癌作用，其Ki 值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力，在体外表现出遗传毒性。
TN3695	Coniine hydrochloride	Others	Others
	Coniine hydrochloride 是一种聚酮化合物衍生的生物碱，对人类和动物有毒。它是一种烟碱型乙酰胆碱受体拮抗剂，可抑制神经系统。
T5S2178	Fargesin 辛夷脂素,(+/-)-Fargesin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fargesin ((+/-)-Fargesin) 是一种活性新木脂素，从木兰植物中分离得到，具有抗高血压和抗炎活性。
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天然产物

Guanidinoethyl sulfonate

Cat.No: T21615

Synonym: 脒基牛磺酸,Taurocyamine

Target: Chloride channel

6,2'-Dihydroxyflavone

Cat.No: T8268

Synonym: 6,2-二羟基黄酮,6,2'-二羟基黄酮

Target: GABA Receptor

Cat.No: T21499

Synonym: Latrepirdine,Dimebon,Dimebone

Target: 5-HT Receptor

Protopanaxatriol

Cat.No: T3917

Synonym: 20(R)-APPT,20(R)-Protopanaxatriol,原人参三醇,(20R)-Protopanaxatriol

Target: PPAR

(-)-Coclaurine hydrochloride

Cat.No: TN1519L

Synonym: (-)-Coclaurine hydrochloride (486-39-5 Free base)

Target: AChR

Cat.No: TQ0197

Synonym: 醋硝香豆素,新抗凝

Cat.No: T19713

Synonym: 2-庚基-4-喹啉酮,2-heptylquinolin-4(1H)-one

Target: Others

Cat.No: T3S2100

Synonym: 一叶秋碱,Securinine

Target: GABA Receptor

7-Amino-4-(trifluoromethyl)coumarin

Cat.No: TJS0341

Synonym: 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素

Target: 5-HT Receptor

Cat.No: T7177

Target: Apoptosis, TRP/TRPV Channel

Cat.No: T2751

Synonym: BN-52021,银杏内酯B

Target: Apoptosis, PAFR, Endogenous Metabolite

γ-Linolenic Acid methyl ester

Cat.No: T21504

Synonym: Methyl gamma-linolenate,γ-亚麻酸甲酯

Target: LTR

Anisodamine Hydrobromide

Cat.No: T8304

Synonym: 6-Hydroxyhyoscyamine,氢溴酸山莨菪碱

Target: Adrenergic Receptor, AChR

Cat.No: T0525

Synonym: 夫洛丙酮,Phloropropiophenone

Target: 5-HT Receptor, Transferase

Cat.No: T0354

Synonym: 6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,坎利酮,RP-11614,SC14266

Target: Glucocorticoid Receptor, Endogenous Metabolite

Cat.No: TN1465

Target: NOS, 5-HT Receptor, ROS

Cat.No: T3668

Synonym: Norizalpinin,高良姜素,3,5,7-Trihydroxyflavone

Target: ERK, P450, NF-κB, Autophagy

Tolazoline hydrochloride

Cat.No: T1680

Synonym: Imidaline hydrochloride,苯甲唑啉盐酸盐,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)

Target: Adrenergic Receptor

Cat.No: T3379

Synonym: Decoic acid,CAPRIC ACID,Caprynic acid,癸酸

Target: GluR, iGluR

Cat.No: T0970

Synonym: 山莨菪碱,Anisodamine,7β-Hydroxyhyoscyamine,Raceanisodamine,消旋山莨菪碱

Target: Adrenergic Receptor, AChR

Cat.No: T5743

Target: Liver X Receptor

Thiocolchicoside

Cat.No: T2S1464

Synonym: 硫秋水仙苷;噻可撒可,Thiocolchicine 2-glucoside analog,硫秋水仙苷,Coltramyl

Target: Others, GABA Receptor

Cat.No: T20884

Synonym: Hydroxyzine free base,羟嗪

Target: Histamine Receptor

Palonosetron hydrochloride

Cat.No: T1156

Synonym: 盐酸帕洛诺司琼,RS 25259 197,Palonosetron HCl,RS 25259

Target: 5-HT Receptor

Transcrocetinate disodium

Cat.No: TQ0027

Synonym: Disodium trans-crocetinate,藏红花,藏红花酸二钠盐

Target: NMDAR, iGluR

Ifenprodil Tartrate

Cat.No: T1186

Target: Potassium Channel, NMDAR, iGluR

Lobeline hydrochloride

Cat.No: T0268

Synonym: 盐酸洛贝林,α-Lobeline hydrochloride,L-Lobeline hydrochloride

Target: AChR

Cat.No: T2815

Synonym: 葛根素,Kakonein

Target: 5-HT Receptor

Rauwolscine hydrochloride

Cat.No: T4429

Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Target: Adrenergic Receptor

Cat.No: T21165

Synonym: AI3-19560,墙草碱,Pellitorin

Target: TRP/TRPV Channel

Cat.No: T16535

Target: Chloride channel, GABA Receptor

Cat.No: T7939

Synonym: 2-氨基-2-[2-(4-辛基苯基)乙基]-1,3-丙二醇,FTY-720A,FTY-720,芬戈莫德

Target: S1P Receptor, PAK, LPL Receptor

Andrographolide

Cat.No: T2898

Synonym: Andrographis,穿心莲内酯

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Cat.No: T21581L

Synonym: AC 187 Acetate (151804-77-2 Free base)

Target: Amylin Receptor

Cat.No: T2825

Synonym: 环巴胺,11-Deoxojervine

Target: Hedgehog/Smoothened, Endogenous Metabolite, Smo

Cat.No: T3915

Synonym: 人参皂苷Ro,Chikusetsusaponin 5,Polysciasaponin P3,人参皂苷 Ro,Chikusetsusaponin V

Target: Calcium Channel, Reductase, Prostaglandin Receptor

Cat.No: T10822

Synonym: Cirsitakaoside

Target: Adenosine Receptor

Cat.No: TN1849

Target: GPR, Bombesin Receptor

Arcaine sulfate

Cat.No: T22583

Target: NMDAR

Cat.No: T7060

Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Target: Others

Cat.No: T3865

Synonym: β-桉叶醇,Beta-Selinenol,beta-桉叶醇

Target: TRP/TRPV Channel, AChR

Cat.No: T6648

Synonym: Gindarine,L-Tetrahydropalmatine,Caseanine,罗通定,(-)-Tetrahydropalmatine

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T5776

Target: Apoptosis, Anti-infection

Cat.No: T6S0109

Synonym: Kashmirine,西贝母碱,Imperialine,西贝碱

Target: Others

Cat.No: TN2247

Target: Adenosine Receptor

Methyl maslinate

Cat.No: TN7129

Synonym: 马斯里酸甲酯,Maslinic acid methyl ester,Crategolic acid methyl ester

Target: Adrenergic Receptor

Cat.No: T5S0273

Synonym: Lenticin,Glyyunnanenine,Tryptophan Betaine,刺桐碱

Target: Others

6-Diazo-5-oxo-L-nor-Leucine

Cat.No: T8373

Synonym: DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine

Target: Influenza Virus, Glutaminase, Antibacterial, Antibiotic

Coniine hydrochloride

Cat.No: TN3695

Target: Others

Cat.No: T5S2178

Synonym: 辛夷脂素,(+/-)-Fargesin

Target: Adrenergic Receptor

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00484	Cerberus 1/CER1 Protein, Human, Recombinant (His) DAND4,cerberus 1, DAN family BMP antagonist	Human	Baculovirus Insect Cells
	Cerberus 1/CER1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is AAH69371.1.
TMPY-04275	IL-36RN/IL-1F5 Protein, Mouse, Recombinant Fil1δ,AI413231,RP23-176J12.6,Fil1delta,Il1hy1,Il-1h3,interle...	Mouse	E. coli
	IL-36RN/IL-1F5 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is Q9QYY1.
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagonist,ICIL-1...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-05845	IL-1RA Protein, Cynomolgus, Recombinant (His) interleukin 1 receptor antagonist	Cynomolgus	E. coli
	IL-1RA Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.63 kDa and the accession number is Q866R8.
TMPY-05837	IL-1RA Protein, Rat, Recombinant (His) interleukin 1 receptor antagonist	Rat	E. coli
	IL-1RA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.01 kDa and the accession number is A6JSY4.
TMPY-03081	IL-1RA Protein, Rat, Recombinant (hFc) interleukin 1 receptor antagonist	Rat	HEK293 Cells
	IL-1RA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is P25086.
TMPY-02670	NBL1 Protein, Mouse, Recombinant (His) neuroblastoma 1, DAN family BMP antagonist,DAN,NO3,...	Mouse	HEK293 Cells
	NBL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.8 kDa and the accession number is Q61477.
TMPY-00771	NBL1 Protein, Human, Recombinant (hFc) neuroblastoma 1, DAN family BMP antagonist,NO3,NB,D...	Human	HEK293 Cells
	NBL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is P41271-1.
TMPY-01039	NBL1 Protein, Human, Recombinant (His) neuroblastoma 1, DAN family BMP antagonist,NO3,DAN,...	Human	HEK293 Cells
	NBL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.3 kDa and the accession number is P41271-1.
TMPJ-00909	IL-1RA Protein, Mouse, Recombinant IL-1RN,IRAP,Interleukin-1 Receptor Antagonist Prote...	Mouse	E. coli
	Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and I...
TMPY-00852	IL-1RA Protein, Human, Recombinant (hFc) interleukin 1 receptor antagonist,MVCD4,IRAP,IL1RA,...	Human	HEK293 Cells
	IL-1RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is P18510-1.
TMPH-03308	Gremlin-1 Protein, Rat, Recombinant (His & Myc) Down-regulated in Mos-transformed cells protein,Gremlin-1,Cy...	Rat	HEK293 Cells
	Gremlin-1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293.
TMPY-00847	IL-36RN/IL-1F5 Protein, Human, Recombinant IL1L1,IL1F5,FIL1,interleukin 36 receptor antagonist...	Human	E. coli
	IL-36RN/IL-1F5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.1 kDa and the accession number is Q9UBH0.
TMPJ-00418	TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His) Decoy Receptor 1,Antagonist Decoy Receptor for TRAI...	Human	HEK293 Cells
	Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
TMPK-00925	Noggin/NOG Protein, Mouse, Recombinant NOG,SYM1,SYNS1,Noggin	Mouse	HEK293 Cells
	Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG...
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells) interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPJ-01065	Noggin/NOG Protein, Mouse, Recombinant (His) Nog,Noggin	Mouse	HEK293 Cells
	Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi...
TMPH-01952	SPRY2 Protein, Human, Recombinant (His & Myc) Protein sprouty homolog 2,SPRY2	Human	E. coli
	Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2. Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis. Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells. Inhibits CBL/C-CBL-mediated EGFR ubiquitination. SPRY2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expressio...
TMPJ-00742	GCG Protein, Human, Recombinant (His) Glicentin,GRPP,GLP-2,Glucagon-Like Peptide 1,OXM,Glucagon,GL...	Human	HEK293 Cells
	Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin....
TMPK-00806	GHR/Growth Hormone R Protein, Human, Recombinant (His) GHR/BP,GH receptor,GHBP,GHR	Human	HEK293 Cells
	Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
TMPJ-00119	IL-22RA2 Protein, Human, Recombinant (hFc) Cytokine Receptor Family 2 Member 10,CRF2-10,IL-22RA2,Interl...	Human	HEK293 Cells
	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
TMPK-00156	DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi) Dickkopf-1,Dkk1,hDkk-1,hDkk1,Dkk-1,SK,Dickkopf-related 1	Human	HEK293 Cells
	Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.
TMPK-00158	DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated hDkk1,Dkk1,Dickkopf-1,Dkk-1,Dickkopf-related 1,SK,hDkk-1	Human	HEK293 Cells
	Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.
TMPK-00155	DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi) hDkk-1,Dickkopf-1,Dkk1,hDkk1,SK,Dkk-1,Dickkopf-related 1	Human	HEK293 Cells
	Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 38.69 kDa and the accession number is O94907.
TMPK-01152	CHRDL1 Protein, Human, Recombinant (His) VOPT,Ventroptin,Neuralin-1,dA141H5.1,CHL,Chordin-like 1,CRDL...	Human	E. coli
	CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant.
TMPH-01595	KMO Protein, Human, Recombinant (His) Kynurenine 3-monooxygenase,KMO,Kynurenine 3-hydroxylase	Human	E. coli
	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).
TMPK-00157	DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated hDkk-1,SK,Dkk1,Dickkopf-related 1,Dickkopf-1,Dkk-1,hDkk1	Human	HEK293 Cells
	Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 38.69 kDa and the accession number is O94907.
TMPY-01755	VWC2 Protein, Human, Recombinant (His) PSST739,von Willebrand factor C domain containing 2,UNQ739	Human	HEK293 Cells
	Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neura...
TMPH-01597	KYAT1 Protein, Human, Recombinant (His & SUMO) Kynurenine aminotransferase 1,KYAT1,Glutamine--phenylpyruvat...	Human	E. coli
	Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cl...
TMPK-00926	Noggin/NOG Protein, Mouse, Recombinant (His & Flag) SYNS1,NOG,SYM1,Noggin	Mouse	HEK293 Cells
	Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG...
TMPJ-00513	LTF Protein, Human, Recombinant (His) Lactoferroxin-A,Talalactoferrin,LTF,Lactotransferrin,Lactofe...	Human	HEK293 Cells
	Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-...
TMPJ-00238	Lefty-A Protein, Human, Recombinant (His) Endometrial bleeding-associated factor,TGFB4,TGF-β-4,EBAF,LE...	Human	HEK293 Cells
	Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma cells. Its mRNA expression on the left side of the developing embryo earned the name “Lefty”. The human orthologue was initially identified as Ebaf, Endometrial bleeding associated factor. Lefty contains the six cysteine residues that are conserved among TGF-β related proteins a...
TMPY-03963	CALCB Protein, Human, Recombinant (mFc) CGRP-II,calcitonin-related polypeptide β,calcitonin-related ...	Human	HEK293 Cells
	CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, blood, and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS), of ...
TMPY-00186	GHRH Protein, Human, Recombinant (hFc) GRF,INN,growth hormone releasing hormone,GHRF	Human	HEK293 Cells
	The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl...
TMPY-03046	APCDD1 Protein, Human, Recombinant (hFc) HYPT1,B7323,adenomatosis polyposis coli down-regulated 1,HTS...	Human	HEK293 Cells
	Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, respectively. Mechanistically, this was due to increased levels of methylation in the promoter region of the APCDD1 gene. Consistently, the DNA methyltransferase inhibitor 5-AZA-dC, reduced DNA methylation in the APCDD1 promoter, and restored APCDD1 expression in OS tissue and cells...

重组蛋白

Cerberus 1/CER1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00484

Species: Human

Expression System: Baculovirus Insect Cells

IL-36RN/IL-1F5 Protein, Mouse, Recombinant

Cat.No: TMPY-04275

Species: Mouse

Expression System: E. coli

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

IL-1RA Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05845

Species: Cynomolgus

Expression System: E. coli

IL-1RA Protein, Rat, Recombinant (His)

Cat.No: TMPY-05837

Species: Rat

Expression System: E. coli

IL-1RA Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03081

Species: Rat

Expression System: HEK293 Cells

NBL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02670

Species: Mouse

Expression System: HEK293 Cells

NBL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00771

Species: Human

Expression System: HEK293 Cells

NBL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01039

Species: Human

Expression System: HEK293 Cells

IL-1RA Protein, Mouse, Recombinant

Cat.No: TMPJ-00909

Species: Mouse

Expression System: E. coli

IL-1RA Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00852

Species: Human

Expression System: HEK293 Cells

Gremlin-1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03308

Species: Rat

Expression System: HEK293 Cells

IL-36RN/IL-1F5 Protein, Human, Recombinant

Cat.No: TMPY-00847

Species: Human

Expression System: E. coli

TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00418

Species: Human

Expression System: HEK293 Cells

Noggin/NOG Protein, Mouse, Recombinant

Cat.No: TMPK-00925

Species: Mouse

Expression System: HEK293 Cells

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-01099

Species: Human

Expression System: HEK293 Cells

Noggin/NOG Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01065

Species: Mouse

Expression System: HEK293 Cells

SPRY2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01952

Species: Human

Expression System: E. coli

GCG Protein, Human, Recombinant (His)

Cat.No: TMPJ-00742

Species: Human

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Human, Recombinant (His)

Cat.No: TMPK-00806

Species: Human

Expression System: HEK293 Cells

IL-22RA2 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00119

Species: Human

Expression System: HEK293 Cells

DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)

Cat.No: TMPK-00156

Species: Human

Expression System: HEK293 Cells

DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPK-00158

Species: Human

Expression System: HEK293 Cells

DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi)

Cat.No: TMPK-00155

Species: Human

Expression System: HEK293 Cells

CHRDL1 Protein, Human, Recombinant (His)

Cat.No: TMPK-01152

Species: Human

Expression System: E. coli

KMO Protein, Human, Recombinant (His)

Cat.No: TMPH-01595

Species: Human

Expression System: E. coli

DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPK-00157

Species: Human

Expression System: HEK293 Cells

VWC2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01755

Species: Human

Expression System: HEK293 Cells

KYAT1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01597

Species: Human

Expression System: E. coli

Noggin/NOG Protein, Mouse, Recombinant (His & Flag)

Cat.No: TMPK-00926

Species: Mouse

Expression System: HEK293 Cells

LTF Protein, Human, Recombinant (His)

Cat.No: TMPJ-00513

Species: Human

Expression System: HEK293 Cells

Lefty-A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00238

Species: Human

Expression System: HEK293 Cells

CALCB Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03963

Species: Human

Expression System: HEK293 Cells

GHRH Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00186

Species: Human

Expression System: HEK293 Cells

APCDD1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03046

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T40376	L-Phenylalanine-15N L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
T70332	JNJ-61393215
	JNJ-61393215 is a novel selective orexin-1 receptor (OX1R) antagonist.
T69673	Deucrictibant
	Deucrictibant is a bradykinin receptor antagonist.
TMIH-0314	Lurasidone-d8 HCl
	Lurasidone-d8 HCl 是 Lurasidone HCl 的氘代化合物。Lurasidone HCl 的 CAS 号为 367514-88-3。Lurasidone hydrochloride 是多巴胺 D2和5-HT7的拮抗剂，IC50值分别为 1.68 和 0.495 nM，用于治疗精神分裂症和双相情感障碍。它也是5-HT1A受体的部分激动剂，IC50值为 6.75 nM。
T12442	Phenindione D5 Rectadione D5,苯茚二酮 D5	Others	Others
	Phenindione D5 is deuterium labeled Phenindione, which functions as a Vitamin K antagonist.
T11592	Hydroxyzine D8	Others	Others
	Hydroxyzine D8, a deuterium-labeled version of Hydroxyzine, acts as a histamine H1-receptor antagonist.
T11675	Irbesartan-d4 厄贝沙坦 D4,SR-47436 D4,BMS-186295 D4	Others	Others
	Irbesartan D4, a deuterium-labeled variant of Irbesartan, is a highly potent and specific antagonist of the angiotensin II type 1 (AT1) receptor.
T11536	Haloperidol (D4') Haloperidol D4',氟哌啶醇 (D4')	Others	Others
	Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist.
T11869	Losartan (D4 Carboxylic Acid) E-3174 D4,氯沙坦羧酸 D4,EXP-3174 D4	Others	Others
	Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.
T10181	6-beta-Naloxol D5 hydrochloride 6β-Naloxol D5 hydrochloride	Others	Others
	6-beta-Naloxol D5 hydrochloride is a deuterium-labeled opioid antagonist, closely related to naloxone, that serves as an effective compound in the field of chemical research.
T12631	(R)-Mirtazapine D3 (R)-6-Azamianserin D3,(R)-Org3770 D3	5-HT Receptor	GPCR/G Protein; Neuroscience
	(R)-Mirtazapine D3 is a deuterium labeled (R)-Mirtazapine.(R)-Mirtazapine is a antagonist of 5-HT3 receptor.
T11591	Hydroxyzine D4 羟嗪 D4	Others	Others
	Hydroxyzine D4 is a deuterium-labeled variation of Hydroxyzine, a chemical compound known for its anticholinergic, anxiolytic, and analgesic properties. It is classified as a heterocyclic histamine H1-receptor antagonist.
T12806	(S)-Mirtazapine D3 (S)-Org3770 D3,(S)-6-Azamianserin D3	5-HT Receptor	GPCR/G Protein; Neuroscience
	(S)-Mirtazapine D3 is a deuterium labeled (S)-Mirtazapine. (S)-Mirtazapine is a stereoselective antagonist of 5-HT2 receptor. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2.
T10241	Acrivastine D7 BW825C D7	Others	Others
	Acrivastine D7 is a deuterium labeled Acrivastine. Acrivastine is a short acting antagonist of histamine 1 receptor.
TMIJ-0172	Mifepristone-d6
	Mifepristone-d6 是 Mifepristone 的氘代化合物。Mifepristone 的 CAS 号为 84371-65-3。Mifepristone 是一种黄体酮受体和糖皮质激素受体拮抗剂，在体外实验中的IC50值分别为 0.2 nM 和 2.6 nM。
T10670	Candesartan-d4 坎地沙坦 D4,CV-11974 D4	Others	Others
	Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.
T12300	Olmesartan-d4 RNH-6270 D4,奥美沙坦 D4	Others	Others
	Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.
T10559	Blonanserin D8 AD-5423 D8	Others	Others
	Blonanserin D8 is a deuterium-labeled Blonanserin. Blonanserin (AD-5423) is a dopamine D2/5-HT2 receptor antagonist with an atypical antipsychotic effect.
T19190	Alosetron D3 Hydrochloride GR-68755C D3	Others	Others
	Alosetron D3 (GR 68755 D3) Hydrochloride is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.
T19233	Cetirizine D4 dihydrochloride Cetirizine D4 dihydrochloride (1219803-84-5 free base)	Others	Others
	Cetirizine D4 dihydrochloride is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
T13432	β-Apo-13-carotenone D3 D'Orenone D3	Others	Others
	β-Apo-13-carotenone D3 is the deuterium labeled β-Apo-13-carotenone. β-Apo-13-carotenone is an antagonist of RXRα.
T19234	Cetirizine D8 dihydrochloride 盐酸西替利嗪 D8	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cetirizine D8 dihydrochloride is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
TMIJ-0213	Naloxone-d5 HCl
	Naloxone-d5 HCl 是 Naloxone HCl 的氘代化合物。Naloxone HCl 的 CAS 号为 357-08-4。Naloxone hydrochloride 是一种特异性、没有激动剂活性的opiate拮抗剂。它是 mu、delta 和 kappa 阿片受体的竞争性拮抗剂。
T11870	Losartan D4 氯沙坦 D4,DuP-753 D4	Others	Others
	Losartan D4, the deuterium-labeled version of Losartan, functions as an angiotensin II receptor antagonist. It inhibits the interaction between angiotensin II and AT1 receptors by competing for binding, achieving an IC50 value of 20 nM.
T11208	Enzalutamide-d3 MDV3100 D3	Others	Others
	Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
T13185	Topiramate D12 RWJ 17021 D12,McN 4853 D12	Others	Others
	Topiramate D12 is a deuterium labeled Topiramate. Topiramate is an agent of broad-spectrum antiepileptic. Topiramate is an antagonist of GluR5 receptor.
T19191	Alosetron-d3 Alosetron D3,GR 68755 D3,GR 68755X D3	Others	Others
	Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.
T10558	Blonanserin D5 AD-5423 D5	Others	Others
	Blonanserin D5 is a deuterium-labeled Blonanserin. Blonanserin (AD-5423) is a dopamine D2/5-HT2 receptor antagonist with an atypical antipsychotic effect.
T12618L	Quetiapine-d4 hemifumarate 半富马酸奎硫平 D4	Others	Others
	Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with ntidepressant and anxiolytic.
T12210	Netupitant D6 CID-6451149 D6	Others	Others
	Netupitant D6 is the deuterium labeled Netupitant, which is a selective and orally active antagonist of neurokinin-1 receptor.
T10113	3-Hydroxy agomelatine D3	5-HT Receptor	GPCR/G Protein; Neuroscience
	3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).
TMID-0022	Spironolactone-d3
	Spironolactone-d3 是 Spironolactone 的氘代化合物。Spironolactone 的 CAS 号为 52-01-7。Abbolactone 是一种可口服的醛固酮盐皮质激素受体拮抗剂，IC50值为 24 nM。它也是雄激素受体拮抗剂，促进足细胞自噬，IC50值为 77 nM。
T12618	Quetiapine-d4 fumarate Quetiapine D4 fumarate,富马酸奎硫平 D4	Others	Others
	Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with antidepressant and anxiolytic.
T12550	Propranolol-d7 hydrochloride Propranolol D7 hydrochloride	Others	Others
	Propranolol D7 hydrochloride is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective antagonist of β-adrenergic receptor (βAR).
T10440	Azilsartan-d5 TAK-536 D5	Others	Others
	Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.
T10770	Cetirizine D8	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cetirizine D8 is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
T10769	Cetirizine D4	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cetirizine D4 is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
TMIJ-0112	Aripiprazole-d8
	Aripiprazole-d8 是 Aripiprazole 的氘代化合物。Aripiprazole 的 CAS 号为 129722-12-9。Aripiprazole 是血清素受体 5-HT1A 和多巴胺 D2 受体的部分激动剂，还用作突触后拮抗剂和血清素受体 5-HT2A 的拮抗剂。
T13400	Ziprasidone D8 CP-88059 D8	Others	Others
	Ziprasidone D8 is deuterium labeled Ziprasidone, which is a antagonist of combined 5-HT (serotonin) and dopamine receptor and exhibits potent effects of antipsychotic activity.
T12973	Solifenacin D5 hydrochloride	Others	Others
	Solifenacin D5 hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is an antagonist of muscarinic receptor(pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively).
T10351	Aprocitentan D4 ACT-132577 D4	Others	Others
	Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5).
TMID-0197	Metoprolol-d6
	Metoprolol-d6 是 Metoprolol 的氘代化合物。Metoprolol 的 CAS 号为 51384-51-1。
TMID-0125	Canrenone-d4
	Canrenone-d4 是 Canrenone 的氘代化合物。Canrenone 的 CAS 号为 976-71-6。Canrenone 是一种醛固酮 (aldosterone) 拮抗剂，广泛用作利尿剂。
T13282	Valsartan-d9 CGP-48933 D9,缬沙坦 D9	Others	Others
	Valsartan D9 is a deuterium-labeled valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure.
T10229	Acebutolol D7	Others	Others
	Acebutolol D7 is a deuterium-labeled Acebutolol. Acebutolol is a selective antagonist of the β1 adrenergic receptor used in the treatment of angina pectoris, hypertension, and cardiac arrhythmias.
TMIH-0573	Thiothixene-d8 P2
	Thiothixene-d8 P2 是 Thiothixene 的氘代化合物。Thiothixene 的 CAS 号为 3313-26-6。(Z)-Thiothixene 是一种血清素受体拮抗剂。
TMIH-0572	Thiothixene-d8 P1
	Thiothixene-d8 P1 是 Thiothixene 的氘代化合物。Thiothixene 的 CAS 号为 3313-26-6。(Z)-Thiothixene 是一种血清素受体拮抗剂。
TMID-0124	Canrenone-d6
	Canrenone-d6 是 Canrenone 的氘代化合物。Canrenone 的 CAS 号为 976-71-6。Canrenone 是一种醛固酮 (aldosterone) 拮抗剂，广泛用作利尿剂。
T11295	Flibanserin-d4 BIMT-17BS D4,BIMT-17 D4,Flibanserin D4	Others	Others
	Flibanserin, a compound identified as BIMT-17, acts as a complete agonist at the serotonin 5-HT1A receptor, with a binding affinity (Ki) of 1 nM, while functioning as an antagonist at the 5-HT2A receptor with a 49 nM affinity. Flibanserin D4 represents a deuterium-labeled version of Flibanserin.
TMIH-0094	Apalutamide-d7
	Apalutamide-d7 是 Apalutamide 的氘代化合物。Apalutamide 的 CAS 号为 956104-40-8。Apalutamide 是一种有效、竞争性的雄激素受体 (AR) 拮抗剂(IC50:16 nM)。
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同位素标记化合物

L-Phenylalanine-15N

Cat.No: T40376

Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Target: Calcium Channel

Cat.No: T70332

Cat.No: T69673

Lurasidone-d8 HCl

Cat.No: TMIH-0314

Cat.No: T12442

Synonym: Rectadione D5,苯茚二酮 D5

Target: Others

Cat.No: T11592

Target: Others

Cat.No: T11675

Synonym: 厄贝沙坦 D4,SR-47436 D4,BMS-186295 D4

Target: Others

Haloperidol (D4')

Cat.No: T11536

Synonym: Haloperidol D4',氟哌啶醇 (D4')

Target: Others

Losartan (D4 Carboxylic Acid)

Cat.No: T11869

Synonym: E-3174 D4,氯沙坦羧酸 D4,EXP-3174 D4

Target: Others

6-beta-Naloxol D5 hydrochloride

Cat.No: T10181

Synonym: 6β-Naloxol D5 hydrochloride

Target: Others

(R)-Mirtazapine D3

Cat.No: T12631

Synonym: (R)-6-Azamianserin D3,(R)-Org3770 D3

Target: 5-HT Receptor

Cat.No: T11591

Synonym: 羟嗪 D4

Target: Others

(S)-Mirtazapine D3

Cat.No: T12806

Synonym: (S)-Org3770 D3,(S)-6-Azamianserin D3

Target: 5-HT Receptor

Cat.No: T10241

Synonym: BW825C D7

Target: Others

Mifepristone-d6

Cat.No: TMIJ-0172

Cat.No: T10670

Synonym: 坎地沙坦 D4,CV-11974 D4

Target: Others

Cat.No: T12300

Synonym: RNH-6270 D4,奥美沙坦 D4

Target: Others

Cat.No: T10559

Synonym: AD-5423 D8

Target: Others

Alosetron D3 Hydrochloride

Cat.No: T19190

Synonym: GR-68755C D3

Target: Others

Cetirizine D4 dihydrochloride

Cat.No: T19233

Synonym: Cetirizine D4 dihydrochloride (1219803-84-5 free base)

Target: Others

β-Apo-13-carotenone D3

Cat.No: T13432

Synonym: D'Orenone D3

Target: Others

Cetirizine D8 dihydrochloride

Cat.No: T19234

Synonym: 盐酸西替利嗪 D8

Target: Histamine Receptor

Naloxone-d5 HCl

Cat.No: TMIJ-0213

Cat.No: T11870

Synonym: 氯沙坦 D4,DuP-753 D4

Target: Others

Enzalutamide-d3

Cat.No: T11208

Synonym: MDV3100 D3

Target: Others

Cat.No: T13185

Synonym: RWJ 17021 D12,McN 4853 D12

Target: Others

Cat.No: T19191

Synonym: Alosetron D3,GR 68755 D3,GR 68755X D3

Target: Others

Cat.No: T10558

Synonym: AD-5423 D5

Target: Others

Quetiapine-d4 hemifumarate

Cat.No: T12618L

Synonym: 半富马酸奎硫平 D4

Target: Others

Cat.No: T12210

Synonym: CID-6451149 D6

Target: Others

3-Hydroxy agomelatine D3

Cat.No: T10113

Target: 5-HT Receptor

Spironolactone-d3

Cat.No: TMID-0022

Quetiapine-d4 fumarate

Cat.No: T12618

Synonym: Quetiapine D4 fumarate,富马酸奎硫平 D4

Target: Others

Propranolol-d7 hydrochloride

Cat.No: T12550

Synonym: Propranolol D7 hydrochloride

Target: Others

Cat.No: T10440

Synonym: TAK-536 D5

Target: Others

Cat.No: T10770

Target: Histamine Receptor

Cat.No: T10769

Target: Histamine Receptor

Aripiprazole-d8

Cat.No: TMIJ-0112

Cat.No: T13400

Synonym: CP-88059 D8

Target: Others

Solifenacin D5 hydrochloride

Cat.No: T12973

Target: Others

Aprocitentan D4

Cat.No: T10351

Synonym: ACT-132577 D4

Target: Others

Cat.No: TMID-0197

Cat.No: TMID-0125

Cat.No: T13282

Synonym: CGP-48933 D9,缬沙坦 D9

Target: Others

Cat.No: T10229

Target: Others

Thiothixene-d8 P2

Cat.No: TMIH-0573

Thiothixene-d8 P1

Cat.No: TMIH-0572

Cat.No: TMID-0124

Cat.No: T11295

Synonym: BIMT-17BS D4,BIMT-17 D4,Flibanserin D4

Target: Others

Cat.No: TMIH-0094

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