DCG-IV

Name: DCG-IV
Brand: TargetMol
SKU: T10978
Rating: 4.5 (1 reviews)

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产品编号 T10978Cas号 147782-19-2

DCG-IV is an effective agonist of class II mGluR. DCG-IV has anticonvulsant and neuroprotective effects. The EC50 of mGlu2R and mGlu3R are 0.35 and 0.09 μM, respectively. DCG-IV is also a competitive antagonist of Group I (IC50: mGlu1 / 5R = 389/630 μM) and III receptor (IC50: mGlu4 / 6/7 / 8R = 22.5 / 39.6 / 40.1 / 32 μM).

DCG-IV

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产品编号 T10978Cas号 147782-19-2

规格	价格	库存
1 mg	¥ 5,210	35日内发货
10 mg	¥ 11,100	35日内发货
50 mg	¥ 44,900	35日内发货

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产品描述	DCG-IV is an effective agonist of class II mGluR. DCG-IV has anticonvulsant and neuroprotective effects. The EC50 of mGlu2R and mGlu3R are 0.35 and 0.09 μM, respectively. DCG-IV is also a competitive antagonist of Group I (IC50: mGlu1 / 5R = 389/630 μM) and III receptor (IC50: mGlu4 / 6/7 / 8R = 22.5 / 39.6 / 40.1 / 32 μM).
靶点活性	mGluR2R:0.35 μM (EC50), mGluR6:39.6 μM (IC50), mGluR3R:0.09 μM (EC50), mGluR1R:389 μM (IC50), mGluR5:630 μM (IC50), mGluR8:32 μM (IC50), mGluR4R:22.5 μM (IC50), mGluR7:40.1 μM (IC50)
体外活性	DCG-IV is also a NMDA receptor agonist in rat cerebral cortex.
体内活性	DCG-IV (1-10 mg / kg; i.p.) inhibits hyperactivity caused by phencyclidine (PCP).