购物车
- 全部删除
- 您的购物车当前为空
(±)-Penbutolol ((Rac)-Penbutolol) 属于Penbutolol的外消旋体。作为一种β-肾上腺素受体拮抗剂,其具备口服活性。该化合物能有效抑制运动引起的心动过速,降低运动时的峰值呼气流量(PEFR)并在静息状态下减少肾素活性(PRA)。服用后1小时内,(±)-Penbutolol在血液中达到峰值浓度,半衰期为4.5小时,并转化为活性代谢物。该化合物常用于心血管病的相关研究。
(±)-Penbutolol ((Rac)-Penbutolol) 属于Penbutolol的外消旋体。作为一种β-肾上腺素受体拮抗剂,其具备口服活性。该化合物能有效抑制运动引起的心动过速,降低运动时的峰值呼气流量(PEFR)并在静息状态下减少肾素活性(PRA)。服用后1小时内,(±)-Penbutolol在血液中达到峰值浓度,半衰期为4.5小时,并转化为活性代谢物。该化合物常用于心血管病的相关研究。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | (±)-Penbutolol ((Rac)-Penbutolol) is the racemic form of Penbutolol. It acts as an orally active β-adrenergic receptor antagonist. (±)-Penbutolol mitigates the tachycardia induced by exercise, reduces the increase in peak expiratory flow rate (PEFR) caused by physical activity, and decreases plasma renin activity (PRA) at rest. The peak plasma concentration of this compound is achieved one hour after oral administration, with a half-life of 4.5 hours, and it is metabolized into active metabolites in the body. This compound is utilized in research related to cardiovascular diseases. |
别名 | (Rac)-Penbutolol, (±)-Isopenbutolol |
分子量 | 291.43 |
分子式 | C18H29NO2 |
CAS No. | 36507-48-9 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
评论内容