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JMV3002
还可以产品编号 T35793Cas号 925239-03-8
别名 JMV3002
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg.
JMV3002
还可以产品编号 T35793 别名 JMV3002Cas号 925239-03-8
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | 待估 | 35日内发货 | |
| 500 μg | 待估 | 35日内发货 | |
| 1 mg | 待估 | 35日内发货 | |
| 5 mg | 待估 | 35日内发货 |
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产品介绍
生物活性
化学信息
| 产品描述 | Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg. |
| 别名 | JMV3002 |
| 分子量 | 586.68 |
| 分子式 | C35H34N6O3 |
| CAS No. | 925239-03-8 |
| 密度 | 1.25 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL (0.43 mM), Sonication is recommended. DMSO: 20 mg/mL (34.09 mM), Sonication is recommended. DMF: 30 mg/mL (51.14 mM), Sonication is recommended. Ethanol: 30 mg/mL (51.14 mM), Sonication is recommended. |
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