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AC-178335 is a pure somatostatin (SRIF) antagonist with an affinity constant (Ki) of 172 +/- 12 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50 = 5.1 +/- 1.4 microM). It induces GH release when given alone (50 micrograms intravenously) to anesthetized rats with or without pretreatment with a long-acting SRIF agonist.
AC-178335 is a pure somatostatin (SRIF) antagonist with an affinity constant (Ki) of 172 +/- 12 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50 = 5.1 +/- 1.4 microM). It induces GH release when given alone (50 micrograms intravenously) to anesthetized rats with or without pretreatment with a long-acting SRIF agonist.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 期货 |
产品描述 | AC-178335 is a pure somatostatin (SRIF) antagonist with an affinity constant (Ki) of 172 +/- 12 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50 = 5.1 +/- 1.4 microM). It induces GH release when given alone (50 micrograms intravenously) to anesthetized rats with or without pretreatment with a long-acting SRIF agonist. |
别名 | AC178335, AC 178335 |
分子量 | 946.11 |
分子式 | C49H63N13O7 |
CAS No. | 212966-15-9 |
密度 | 1.36 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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