ADTN hydrobromide

Name: ADTN hydrobromide
Brand: TargetMol
SKU: T37150
Rating: 4.5 (1 reviews)

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产品编号 T37150Cas号 13575-86-5

ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM.

ADTN hydrobromide

还可以

产品编号 T37150Cas号 13575-86-5

规格	价格	库存
5 mg	¥ 686	35日内发货
25 mg	¥ 2,970	35日内发货
50 mg	¥ 5,440	35日内发货

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产品介绍

生物活性

产品描述	ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM.
体内活性	In vivo, 6,7-ADTN induces hyperlocomotion in rats when injected bilaterally at a dose of 100 nmol per side into the nucleus accumbens. It increases cAMP production and glycoprotein secretion in the albumen gland of H. duryi (snail). It also reduces sucrose feeding in R. maderae (cockroach) nymphs.

化学信息

分子量	260.13
分子式	C₁₀H₁₄BrNO₂
CAS No.	13575-86-5

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

H2O: 100 mM, Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	3.8442 mL	19.2212 mL	38.4423 mL	192.2116 mL
5 mM	0.7688 mL	3.8442 mL	7.6885 mL	38.4423 mL
10 mM	0.3844 mL	1.9221 mL	3.8442 mL	19.2212 mL
20 mM	0.1922 mL	0.9611 mL	1.9221 mL	9.6106 mL
50 mM	0.0769 mL	0.3844 mL	0.7688 mL	3.8442 mL
100 mM	0.0384 mL	0.1922 mL	0.3844 mL	1.9221 mL