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LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).
LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 17,200 | 10-14周 | |
50 mg | ¥ 22,800 | 10-14周 | |
100 mg | ¥ 29,500 | 10-14周 |
产品描述 | LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM). |
靶点活性 | LTD4:0.57 nM (ki) |
体外活性 | LTD4 antagonist 1 (Compound 38b) shows a Ki of 0.57 nM for the displacement of [3H]LTD4 on guinea pig lung membranes, a pKB of 9.93 versus LTE4 on guinea pig trachea. |
体内活性 | LTD4 antagonist 1 shows a ED50 (i.v.)/ED50 (p.o.) of 0.036 and 1.44 μmol/kg in LTD4-induced bronchoconstriction in guinea pigs. |
分子量 | 615.66 |
分子式 | C31H32F3N3O5S |
CAS No. | 136564-67-5 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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