SKF 100398

Name: SKF 100398
Brand: TargetMol
SKU: T40884
Rating: 4.5 (1 reviews)

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产品编号 T40884Cas号 77453-01-1

别名 d(CH2)5Tyr(Et)VAVP

SKF 100398, also known as d(CH2)5Tyr(Et)VAVP, is a particular analog of arginine vasopressin (AVP). It acts as a specific antagonist, specifically targeting the antidiuretic effect caused by both exogenous and endogenous AVP.

SKF 100398

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产品编号 T40884 别名 d(CH2)5Tyr(Et)VAVPCas号 77453-01-1

规格	价格	库存	数量
25 mg	¥ 10,600	待询

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产品介绍

生物活性

产品描述	SKF 100398, also known as d(CH2)5Tyr(Et)VAVP, is a particular analog of arginine vasopressin (AVP). It acts as a specific antagonist, specifically targeting the antidiuretic effect caused by both exogenous and endogenous AVP.
体内活性	SKF 100398 is a specific antagonist of the hydrosmotic effect of exogenous and endogenous AVP[1]. SKF 100398 (8 μg/kg; i.v.) abolishes the antidiuretic effect of AVP[1]. Animal Model: Male Sprague-Dawley rats (250-300 g)[1]Dosage: 8 μg/kg Administration: Intravenous injection Result: Completely blocked the antidiuretic effect of exogenous AVP (4 ng/kg body wt i.v.).
别名	d(CH2)5Tyr(Et)VAVP

化学信息

分子量	1136.4
分子式	C₅₃H₇₇N₁₃O₁₁S₂
CAS No.	77453-01-1
密度	1.44g/cm3
Sequence	{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-Phe-Val-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: 1-Cys6)
Sequence Short	{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-YFVNCPRG-NH2 (Disulfide bridge: 1-Cys6)