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AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.
AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 2,190 | 5日内发货 | |
5 mg | ¥ 5,570 | 5日内发货 | |
10 mg | ¥ 8,550 | 5日内发货 | |
25 mg | ¥ 10,700 | 5日内发货 | |
50 mg | ¥ 13,800 | 5日内发货 | |
100 mg | ¥ 17,500 | 5日内发货 | |
1 mL x 10 mM (in DMSO) | ¥ 6,130 | 5日内发货 |
产品描述 | AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1. |
体内活性 | Tumor growth inhibition is statistically significant with AHR antagonist 5 as single. AHR antagonist 5 (10 mg/kg; p.o.; every day for 3 weeks) combination with anti-PD-1 significantly inhibited tumor growth inhibition compared to the anti-PD-1 alone. |
分子量 | 550.89 |
分子式 | C25H27Cl3FN7 |
CAS No. | 2247953-39-3 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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