AZD4721

Name: AZD4721
Brand: TargetMol
SKU: T38850
Price: 117 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T38850Cas号 1418112-77-2

别名 RIST4721, AZD4721

AZD4721 (RIST4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 ( CXCR2 ). AZD4721 has the potential for the research of inflammatory disease.

AZD4721

还可以

产品编号 T38850 别名 RIST4721, AZD4721Cas号 1418112-77-2

AZD4721 (RIST4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 ( CXCR2 ). AZD4721 has the potential for the research of inflammatory disease.

规格	价格	库存
25 mg	¥ 21,500	6-8周
50 mg	¥ 33,300	6-8周
100 mg	¥ 53,400	6-8周

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生物活性

产品描述	AZD4721 (RIST4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 ( CXCR2 ). AZD4721 has the potential for the research of inflammatory disease.
体内活性	Assessment of Pharmacokinetics (PK) profile of AZD4721 (RIST4721) in rat and dog[1]. In Vivo PK Rat Dog Predicted hepatic metabolic CL (ml/min per kilogram) 1.7 0.80 Observed CL (ml/min per kilogram) 2.4 0.50 CL renal (mL/min per kilogram) <0.01 <0.01 CL biliary (mL/min per kilogram) <0.01 0.04 In vivo/in vitro unbound CL int c 1.4 0.6 V SS (l/kg) 0.19 0.15 T 1/2 (h) (PO) 1.3 3.7 (2.7) (8.4) F (%) 45 82
别名	RIST4721, AZD4721