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Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.
Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 367 | 35日内发货 | |
5 mg | ¥ 1,550 | 35日内发货 | |
10 mg | ¥ 2,740 | 35日内发货 | |
50 mg | ¥ 11,900 | 35日内发货 |
产品描述 | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM. |
别名 | CAY10448 |
分子量 | 433.32 |
分子式 | C18H28INO3 |
CAS No. | 1177195-52-6 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | Ethanol: 30 mg/mL Ethanol:PBS (pH 7.2)(1:2): 0.25 mg/mL DMF: 30 mg/mL DMSO: 30 mg/mL |
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