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Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.

Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 532 | 35日内发货 | |
| 5 mg | ¥ 2,230 | 35日内发货 | |
| 10 mg | ¥ 3,970 | 35日内发货 | |
| 50 mg | ¥ 17,200 | 35日内发货 |
| 产品描述 | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM. |
| 别名 | CAY10448 |
| 分子量 | 433.32 |
| 分子式 | C18H28INO3 |
| CAS No. | 1177195-52-6 |
| 密度 | no data available |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度信息 | Ethanol: 30 mg/mL (69.23 mM), Sonication is recommended. Ethanol:PBS (pH 7.2)(1:2): 0.25 mg/mL (0.58 mM), Sonication is recommended. DMF: 30 mg/mL (69.23 mM), Sonication is recommended. DMSO: 30 mg/mL (69.23 mM), Sonication is recommended. |
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