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12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
规格 | 价格 | 库存 | 数量 |
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100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | 12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters. |
别名 | 二氯脱氢松香酸 |
分子量 | 369.33 |
分子式 | C20H26Cl2O2 |
CAS No. | 65281-77-8 |
密度 | 1.200 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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