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ZNU-IMB-Z15(Compound Z15)作为雄激素受体(AR)的拮抗剂和降解剂,能够有效抑制AR阳性去势抵抗性前列腺癌(CRPC)细胞系的增殖并诱导其凋亡(apoptosis),展现出显著的体内外抗癌活性。
ZNU-IMB-Z15(Compound Z15)作为雄激素受体(AR)的拮抗剂和降解剂,能够有效抑制AR阳性去势抵抗性前列腺癌(CRPC)细胞系的增殖并诱导其凋亡(apoptosis),展现出显著的体内外抗癌活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Compound Z15 (ZNU-IMB-Z15) acts as an antagonist and degrader of the androgen receptor (AR). It inhibits the proliferation of castration-resistant prostate cancer (CRPC) cell lines that are AR-positive and induces apoptosis. Compound Z15 exhibits anticancer activity both in vivo and in vitro. |
分子量 | 411.5 |
分子式 | C20H17N3O3S2 |
CAS No. | 920915-26-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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