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α-Conotoxin TxID 为一种有效的α3β4nAChR拮抗剂,IC50为12.5 nM。相对于密切相关的α6/α3β4nAChR,其抑制活性较弱(IC50=94 nM)。此化合物在开发新型戒烟药物方面具有潜力。
α-Conotoxin TxID 为一种有效的α3β4nAChR拮抗剂,IC50为12.5 nM。相对于密切相关的α6/α3β4nAChR,其抑制活性较弱(IC50=94 nM)。此化合物在开发新型戒烟药物方面具有潜力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | α-Conotoxin TxID is a potent antagonist of the α3β4 nicotinic acetylcholine receptor (nAChR), exhibiting an inhibitory half-maximal inhibitory concentration (IC50) of 12.5 nM. Its inhibitory activity against the closely related α6/α3β4 nAChR is weaker, with an IC50 of 94 nM. This compound holds potential for the development of novel smoking cessation drugs [1]. |
分子量 | 1489.79 |
分子式 | C58H92N18O18S5 |
CAS No. | 1496617-64-1 |
存储 | keep away from moisture | Shipping with blue ice. |
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