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O-2050 是一种高亲和力的大麻素CB1受体拮抗剂,Ki 为 2.5 nM。O-2050 抑制大麻素 CB2受体,Ki 为 0.2 nM。O-2050 减少了小鼠的食物摄入量,并且引起小鼠运动。
O-2050 是一种高亲和力的大麻素CB1受体拮抗剂,Ki 为 2.5 nM。O-2050 抑制大麻素 CB2受体,Ki 为 0.2 nM。O-2050 减少了小鼠的食物摄入量,并且引起小鼠运动。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 14,900 | 8-10周 | |
50 mg | ¥ 19,420 | 8-10周 | |
100 mg | ¥ 24,625 | 8-10周 |
产品描述 | O-2050 is a high affinity cannabinoid CB 1 receptor antagonist with a K i of 2.5 nM. O-2050 inhibits cannabinoid CB 2 receptor with Ki of 0.2 nM. O-2050 decreased food intake in mice and caused locomotor stimulation in mice [1]. |
体内活性 | O-2050 (1, 3, 10, 30 mg/kg; ip; pretreatment 30 mins) produces significant and dose-dependent decreases in food intake in mice. O-2050 (10, 30 mg/kg) markedly causes locomotor stimulation [1]. |
分子量 | 417.56 |
分子式 | C23H31NO4S |
CAS No. | 1883545-42-3 |
密度 | 1.173 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | DMSO: <41.76 mg/mL, Sonication is recommended. Ethanol: <41.76 mg/mL, Sonication is recommended. |
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