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Dextromethorphan 是一种非竞争性 NMDA 受体拮抗剂和 sigma-1激动剂,于 1958 年获得 FDA 批准用作止咳药。
Dextromethorphan 是一种非竞争性 NMDA 受体拮抗剂和 sigma-1激动剂,于 1958 年获得 FDA 批准用作止咳药。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mL x 10 mM (in DMSO) | ¥ 1,730 | 现货 |
产品描述 | Dextromethorphan is a noncompetitive NMDA receptor antagonist and sigma-1 agonist that was approved by the FDA in 1958 for use as a cough suppressant. |
体外活性 | 方法:将Dextromethorphan(50-400μM)或LK3(25-200μM)与血小板在37处预孵育3分钟,然后加入诱导剂6分钟以触发TXB2。 结果:用Dextromethorphan治疗可显著抑制TXB2由胶原蛋白刺激的形成。[3] |
别名 | 右美沙芬, RACEMETHORPHAN, Levomethorphan |
分子量 | 271.4 |
分子式 | C18H25NO |
CAS No. | 125-71-3 |
Smiles | O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H] |
密度 | 1.11 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
溶解度信息 | DMSO: 7.33 mg/mL (27.01 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
DMSO
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