|
TMPH-01710
|
Mucolipin-1/MCOLN1 Protein, Human, Recombinant (His)
MCOLN1,MG-2,Mucolipidin,Mucolipin-1,Transient receptor p...
|
Human
|
E. coli
|
|
Mucolipin-1/MCOLN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 66.5 kDa and the accession number is Q9GZU1. |
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TMPH-02905
|
TRPC1 Protein, Mouse, Recombinant (His)
Transient receptor protein 1,Short transient receptor po...
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Mouse
|
E. coli
|
|
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. TRPC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 94.0 kDa and the accession number is Q61056. |
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TMPH-03389
|
TRPA1 Protein, Rat, Recombinant (His & Myc)
Wasabi receptor,Trpa1,Transient receptor potential ...
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Rat
|
E. coli
|
|
TRPA1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.3 kDa and the accession number is Q6RI86. |
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TMPH-03390
|
TRPV2 Protein, Rat, Recombinant (His)
Transient receptor potential cation channel subfami...
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Rat
|
E. coli
|
|
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. TRPV2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 88.2 kDa and th... |
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TMPY-05030
|
PCDH7 Protein, Human, Recombinant (His)
BHPCDH
|
Human
|
Baculovirus Insect Cells
|
|
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number... |
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TMPK-00022
|
Galectin-1 Protein, Human, Recombinant (hFc)
GAL1,LGALS1,Galectin-1,S-Lac lectin 1,DKFZp686E23103,GBP,Gal...
|
Human
|
HEK293 Cells
|
|
Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape. |
|
TMPY-04826
|
LILRB5/CD85c Protein, Human, Recombinant (His)
leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C
|
Human
|
HEK293 Cells
|
|
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig... |
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TMPY-04180
|
PfLDH Protein, P. falciparum, Recombinant (His)
PfLDH,L-lactate dehydrogenase
|
P. falciparum
|
E. coli
|
|
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy. |
|
TMPK-00347
|
Serum Albumin Protein, Human, Recombinant (His & Avi)
Serum albumin,PRO0903,Albumin,PRO1341,ALB,ANALBA,FDAH,PRO088...
|
Human
|
HEK293 Cells
|
|
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. Serum Albumin Protein, Human, Recombinant (His & Avi) is... |
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TMPY-00566
|
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...
|
Human
|
P. pastoris (Yeast)
|
|
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
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TMPY-00545
|
Dermcidin Protein, Human, Recombinant (hFc)
AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP
|
Human
|
HEK293 Cells
|
|
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ... |
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TMPY-00476
|
ITGB1 Protein, Human, Recombinant (His)
VLAB,integrin, beta 1 (fibronectin receptor, beta polypeptid...
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Human
|
HEK293 Cells
|
|
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe... |
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TMPY-02258
|
Kallikrein 3/KLK3 Protein, Human, Recombinant (His)
APS,KLK2A1,PSA,kallikrein related peptidase 3,Hk3
|
Human
|
HEK293 Cells
|
|
KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.... |
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TMPY-01280
|
FOLR2 Protein, Human, Recombinant (His)
FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...
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Human
|
HEK293 Cells
|
|
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc... |
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TMPY-02030
|
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...
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Human
|
HEK293 Cells
|
|
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... |
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TMPY-04544
|
MEK2 Protein, Human, Recombinant (GST)
mitogen-activated protein kinase kinase 2,FLJ26075,MKK2,CFC4...
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Human
|
Baculovirus Insect Cells
|
|
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ... |
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TMPY-01813
|
ACRV1 Protein, Human, Recombinant (His)
SP-10,SPACA2,D11S4365,acrosomal vesicle protein 1
|
Human
|
HEK293 Cells
|
|
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr... |
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TMPY-02219
|
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
NS1 Protein
|
H1N1
|
E. coli
|
|
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As... |
|
TMPK-01485
|
HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein, Human, MHC (His & Avi)
CDHF6,DG3,DSG3,PVA,DSG-3,Desmoglein-3
|
Human
|
HEK293 Cells
|
|
DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. These findings suggest that DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. |
|
TMPY-04022
|
BOLA1 Protein, Human, Recombinant (His)
CGI-143,bolA family member 1
|
Human
|
E. coli
|
|
BOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA1 nullifies the effect of BSO and S-nitrosocysteine on mitochondrial morphology. Conversely, knockdown of the BOLA1 gene increases the oxidation of mitochondrial thiol groups. Supporting a role of BOLA1 in controlling the mitochondrial thiol redox potential is that BOLA1 ortholog... |
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TMPK-00127
|
CLEC4A Protein, Mouse, Recombinant (hFc)
HDCGC13P,Clec4a2,DCIR,CD367,CLECSF6,DCIRLLIR,LLIR,CLEC4A,DDB...
|
Mouse
|
HEK293 Cells
|
|
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.3 kDa and the accession num... |
|
TMPK-00126
|
CLEC4A Protein, Human, Recombinant (hFc)
DCIR,LLIR,CD367,DDB27,CLECSF6,HDCGC13P,DCIRLLIR,Clec4a2,CLEC...
|
Human
|
HEK293 Cells
|
|
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.7 kDa and the accession num... |
|
TMPK-00726
|
DSG3 Protein, Mouse, Recombinant (His)
SG3,PVA,DSG3,CDHF6,Desmoglein-3,DSG-3
|
Mouse
|
HEK293 Cells
|
|
To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Mouse, Recombinant (His) is expressed in HEK2... |
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TMPY-00510
|
FKBP11 Protein, Human, Recombinant (mFc)
FKBP19,FK506 binding protein 11, 19 kDa
|
Human
|
HEK293 Cells
|
|
FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD). FKBP11 during the development of HCC and FKBP11 has the potential to be an early marker for HCC. |
|
TMPK-00871
|
DSG3 Protein, Human, Recombinant (His)
CDHF6,SG3,DSG-3,DSG3,Desmoglein-3,PVA
|
Human
|
HEK293 Cells
|
|
To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK2... |
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TMPJ-01364
|
LMCD1 Protein, Human, Recombinant (His)
LMCD1,Dyxin,LIM and cysteine-rich domains protein 1
|
Human
|
E. coli
|
|
LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critic... |
|
TMPJ-00666
|
CLIC2 Protein, Human, Recombinant (His)
CLIC2,XAP121,Chloride Intracellular Channel Protein 2
|
Human
|
E. coli
|
|
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be d... |
|
TMPK-00994
|
FNDC1 Protein, Human, Recombinant (His)
FNDC2,MEL4B3,KIAA1866
|
Human
|
E. coli
|
|
Fibronectin type III domain‑containing protein 1 (FNDC1) is a protein that contains a major component of the structural domain of fibronectin.FNDC1 was highly upregulated and acted as an oncogene in BC. Therefore, targeting FNDC1 may be a potential strategy for the treatment of BC. |
|
TMPY-03795
|
EIF5A2 Protein, Human, Recombinant (His)
eIF5AII,eukaryotic translation initiation factor 5A2,EIF-5A2
|
Human
|
E. coli
|
|
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic targe... |
|
TMPH-03231
|
AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)
Cysteine-rich antifungal protein 2,Defensin-like protein 2,R...
|
Raphanus sativus
|
E. coli
|
|
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P30230. |
|
TMPY-02660
|
Resistin Protein, Mouse, Recombinant (hFc)
resistin,Xcp4,ADSF,Fizz3,Rstn
|
Mouse
|
HEK293 Cells
|
|
Resistin is an adipocytokine, which has been studied for its role in insulin resistance and recently in inflammation. The RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk. Resistin (RETN), recently found to be relevant to inflammation and inflammatory disorders. |
|
TMPK-00481
|
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta,PDGFRB,PDGFR-2,PDGF-R-β,PDGF-R-beta,PDGFR-β,PDGF...
|
Cynomolgus
|
HEK293 Cells
|
|
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target. |
|
TMPK-00077
|
EPO/Erythropoietin Protein, Human, Recombinant
EPO,MVCD2,红细胞生长素,Epoetin,Erythropoietin,EP
|
Human
|
HEK293 Cells
|
|
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition improvement, neurogenesis, and anti-fibrotic, anti-apoptotic, anti-oxidative, and anti-inflammatory effects. |
|
TMPY-04764
|
PCK2 Protein, Human, Recombinant (His & GST)
PEPCK-M,PEPCK2,PEPCK,phosphoenolpyruvate carboxykinase 2 (mi...
|
Human
|
Baculovirus Insect Cells
|
|
PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabolic switch and the maintenance of TICs in prostate cancer. PCK2 is a potential therapeutic target for aggressive prostate tumors. |
|
TMPK-01517
|
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
survivin variant 3 alpha,MHC I,BIRC5,EPR-1,IAP4,Survivin,API...
|
Human
|
HEK293 Cells
|
|
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
|
TMPK-01480
|
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
IAP4,Survivin,API4,BIRC5,MHC,MHC I,EPR-1,survivin variant 3 ...
|
Human
|
HEK293 Cells
|
|
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
|
TMPJ-00157
|
CD82 Protein, Human, Recombinant (hFc)
Tetraspanin-27,KAI1,ST6,TSPAN27,TSPAN274F9,CD82 molecule,Tsp...
|
Human
|
HEK293 Cells
|
|
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1... |
|
TMPK-01308
|
TAG-72 Protein, Canine, Recombinant (His)
mRNA-methyltransferase,mRNA (guanine-N(7))-methyltransferase...
|
Canine
|
E. coli
|
|
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA synthesis and a potential target for antiviral, antifungal, and antiprotozoal drug discovery. |
|
TMPY-01555
|
PRAC Protein, Human, Recombinant (His & SUMO)
PRAC,C17orf92
|
Human
|
E. coli
|
|
The PRAC gene is located on chromosome 17 at position 17q21, about 4 kbp downstream from the homeodomain Hoxb-13 gene. The pathogenesis of PCa may be due to the expression levels of PRAC protein, and this protein can serve as a potential biomarker for the management of PCa. |
|
TMPK-01516
|
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
IAP4,survivin variant 3 alpha,BIRC5,Survivin,EPR-1,API4,MHC ...
|
Human
|
HEK293 Cells
|
|
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
|
TMPY-05168
|
Syndecan-2 Protein, Mouse, Recombinant (His)
AA960457,4833414L08Rik,Hspg1,Synd2,syndecan 2,syndecan-2
|
Mouse
|
HEK293 Cells
|
|
The key players in the miR-20a-5p/SDC2 axis may be a potential diagnostic biomarker and therapeutic target for OS patients. SDC2 methylation as a blood-based DNA test for early detection of colorectal cancer (CRC). Syndecan-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P43407. |
|
TMPK-01040
|
NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)
NKG2C,NK cell receptor C,CD159c,KLRC2
|
Cynomolgus
|
HEK293 Cells
|
|
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. |
|
TMPK-01042
|
FcRH6/FCRL6 Protein, Human, Recombinant (His)
Fc receptor homolog 6,IFGP6,FcR-like protein 6,FLJ16056,Fc r...
|
Human
|
HEK293 Cells
|
|
Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed that FCRL6 expression by NK- and T-cell subpopulations increases as a function of differentiation and is remarkably restricted to mature lymphocytes with cytotoxic capability. |
|
TMPK-00553
|
ADAM9 Protein, Cynomolgus, Recombinant (His)
Adam9,CORD9,mKIAA0021,Meltrin-γ,Meltrin-gamma,ADAM 9,Mltng,M...
|
Cynomolgus
|
HEK293 Cells
|
|
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS. |
|
TMPK-01318
|
CD24 Protein-VLP, Cynomolgus, Recombinant
MGC75043,CD 24,FLJ43543,FLJ22950,CD24 molecule,CD24A
|
Cynomolgus
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 3.8 kDa and the accession number is XP_015304503.1. |
|
TMPY-04249
|
Syndecan-2 Protein, Human, Recombinant (His)
syndecan 2,HSPG1,CD362,SYND2,HSPG
|
Human
|
HEK293 Cells
|
|
The key players in the miR-20a-5p/SDC2 axis may be a potential diagnostic biomarker and therapeutic target for OS patients. SDC2 methylation as a blood-based DNA test for early detection of colorectal cancer (CRC). Syndecan-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is A0A024R9D1. |
|
TMPH-01595
|
KMO Protein, Human, Recombinant (His)
Kynurenine 3-monooxygenase,KMO,Kynurenine 3-hydroxylase
|
Human
|
E. coli
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Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable). |
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TMPK-00479
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AGER Protein, Cynomolgus, Recombinant (His)
AGER,RAGE,SCARJ1
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Cynomolgus
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HEK293 Cells
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The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer. |
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TMPK-00002
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CD24 Protein, Human, Recombinant (His & Avi)
MGC75043,FLJ22950,CD 24,FLJ43543,CD24A,CD24 molecule
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Human
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HEK293 Cells
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CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 6.5 kDa and the accession number is P25063... |
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TMPK-00708
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TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)
TRAIL R1,APO2,DR4,CD261,TRAIL-R,TNFRSF10A,MGC9365
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Human
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HEK293 Cells
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Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations. |
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