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Imidazole-d4是一种同位素标记的Imidazole,属于杂环芳香族化合物。咪唑类分子被广泛应用于缓蚀剂以及酶抑制剂,如乙酰胆碱酯酶(AChEI)和黄嘌呤氧化酶(XO),并展示出抗真菌、抗结核、抗炎、抗氧化和镇痛等生物活性。此类化合物能够阻止血小板微粒体将内过氧化物(PGG2 和 PGH2)转化为血栓素A2。咪唑衍生物对SARS-CoV-2 3ClPro酶的抑制作用表明其在阿尔茨海默病、痛风、新冠肺炎和血栓疾病等研究中具有潜力。
Imidazole-d4是一种同位素标记的Imidazole,属于杂环芳香族化合物。咪唑类分子被广泛应用于缓蚀剂以及酶抑制剂,如乙酰胆碱酯酶(AChEI)和黄嘌呤氧化酶(XO),并展示出抗真菌、抗结核、抗炎、抗氧化和镇痛等生物活性。此类化合物能够阻止血小板微粒体将内过氧化物(PGG2 和 PGH2)转化为血栓素A2。咪唑衍生物对SARS-CoV-2 3ClPro酶的抑制作用表明其在阿尔茨海默病、痛风、新冠肺炎和血栓疾病等研究中具有潜力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Imidazole-d4 is an isotope-labeled variant of imidazole, which is a heterocyclic aromatic compound. Imidazole molecules serve as inhibitors for acetylcholinesterase (AChEI) and xanthine oxidase (XO) and have been utilized as corrosion inhibitors. They display a range of biological activities, including antifungal, antitubercular, anti-inflammatory, antioxidant, and analgesic properties. Imidazole inhibits platelet microsomes from converting endoperoxides (PGG2 and PGH2) into thromboxane A2. Additionally, imidazole derivatives show inhibitory effects on the SARS-CoV-2 3CLpro enzyme, offering potential for research in Alzheimer’s disease, gout, COVID-19, and thrombotic disorders. |
分子量 | 72.1 |
分子式 | C3H4N2 |
CAS No. | 6923-01-9 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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