Antifungalagent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide targeting Monilinia fructicola. It exhibits antifungal activity with an EC50 of 11.8 mg/L. The mechanism of action involves the disruption of cell membrane integrity, resulting in increased membrane permeability and the release of intracellular electrolytes, which impairs normal mycelial growth. Antifungalagent 106 is also applicable in research related to brown rot in stone fruits.

mTOR:0.8 μM

106 (3.125-50 mg/L) 是一种抗真菌剂,对 M. fructicola 表现出显著的抑制作用.它不仅可以阻止孢子的萌发和菌丝体的形成,还通过诱导过量的内源性活性氧 (ROS) 的产生,在 M. fructicola 中引起了细胞的氧化伤害、酶的失活以及细胞膜的破坏.

在处理梨的植物体时,使用了两种不同浓度的Antifungal agent 106(100 mg/L 和 200 mg/L),喷洒时间持续了24小时.结果显示,处理过的植物体在褐腐病发生率和病斑直径上均有显著降低,证实了Antifungal agent 106对石果褐腐病具有明显的抑制效果.