Kaliotoxin is an inhibitor of neuronal BK-type peptide groups and specifically inhibits Kv channels and calcium-activated potassium channels. Kaliotoxin has research significance on the regulation of cell membrane potential and neuronal excitability. The product number is T37808 and the CAS number is 145199-73-1

Kaliotoxin (250 nM) specifically inhibited the overall Ca2+-activated K+ current in the entire cell. The interaction between Kaliotoxin and KCa channels follows a one-to-one way mechanism with Kd of 20 nM.[1]

Kaliotoxin (10 ng; Male Sprague–Dawley rats; Intracerebroventricular injection) facilitates cognitive processes by the blockage of Kv1.1 or Kv1.3 channels. Improved learning but not information consolidation. Increased the long-term retrieval of an odor-reward association.[2]