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Ferroptosis/apoptosis inducer-1 (compound 4d) 作为一种有效的细胞凋亡 (apoptosis) 和铁死亡 (ferroptosis) 双效诱导剂,通过降低线粒体膜电位并抑制 GPX4 功能来共同促进这两种死亡途径.在实验室研究中,该化合物能显著抑制三阴性乳腺癌 (TNBC) 的增殖和转移,对癌症治疗研究具有极其重要的价值.
Ferroptosis/apoptosis inducer-1 (compound 4d) 作为一种有效的细胞凋亡 (apoptosis) 和铁死亡 (ferroptosis) 双效诱导剂,通过降低线粒体膜电位并抑制 GPX4 功能来共同促进这两种死亡途径.在实验室研究中,该化合物能显著抑制三阴性乳腺癌 (TNBC) 的增殖和转移,对癌症治疗研究具有极其重要的价值.
规格 | 价格 | 库存 | 数量 |
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10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Ferroptosis/apoptosis inducer-1 (compound 4d) acts as a dual inducer of both cell apoptosis (apoptosis) and iron-dependent cell death (ferroptosis). It promotes these processes by decreasing mitochondrial membrane potential and downregulating GPX4. Effective in vitro and in vivo, Ferroptosis/apoptosis inducer-1 significantly inhibits the proliferation and metastasis of triple-negative breast cancer (TNBC), playing a crucial role in cancer research. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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