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TargetMol | Compound Library

疼痛相关化合物库现货

Pain-Related Compound Library

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产品编号 L2690

疼痛是一种与实际或潜在的组织损伤相关的不愉快的感觉和情绪情感体验,或与此相似的经历 ;作为六大生命体征之一,疼痛与呼吸、脉搏、血压、体温等同样重要,反映了身体的健康状态。疼痛按持续时间分为急性疼痛、慢性疼痛;按照病因分为伤害性疼痛和神经病理性疼痛;按感受系统分类表层疼痛、深层疼痛;还可根据来源分为内脏痛和体表痛。 疼痛的产生机制是一个复杂的过程,涉及多个层面,包括生理、心理和神经生物学方面,疼痛主要的机制包括:痛觉感受器的激活,痛觉感受器是分布在皮肤、内脏、骨骼肌和关节等部位的专门感知有害刺激的感觉神经末梢。致痛物质的释放:当组织损伤时,会释放多种致痛物质,如组胺、缓激肽、5-羟色胺、乙酰胆碱、前列腺素等,这些物质能激活痛觉感受器。此外还包括神经信号传导、中枢调控、心理因素等等 TargetMol收集了2780种疼痛相关活性化合物及靶向疼痛相关靶点的化合物,可用于疼痛相关研究。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2690

疼痛相关化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 2780种疼痛相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
  • 结构多样,具有良好的细胞渗透性;
  • 详细的说明书,化合物结构、靶点信息、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

5-HT Receptor
Potassium Channel
Calcium Channel
COX
Histamine Receptor
Sodium Channel
AChR
Autophagy
GABA Receptor
TRP/TRPV Channel
Dopamine Receptor
Apoptosis
Opioid Receptor
Prostaglandin Receptor
Raf
NMDAR
Adrenergic Receptor
p38 MAPK
ERK
Kras
Ras
MAPK
MEK
iGluR
JNK
CDK
S6 Kinase
Norepinephrine
Antibacterial
Neurokinin receptor
Serotonin Transporter
Endothelin Receptor
Src
Parasite
VEGFR
Bradykinin Receptor
NF-κB
PPAR
P450
Lipoxygenase
Akt
Rho
TNF
PKA
Endogenous Metabolite
HER
EGFR
GPR
Sigma receptor
PKC
Aurora Kinase
GluR
Ferroptosis
P2X Receptor
Cannabinoid Receptor
Antibiotic
GSK-3
Drug Metabolite
PDGFR
ROCK
PDE
MNK
Casein Kinase
FLT
c-Kit
MLK
Chloride channel
FAAH
Phospholipase
Carbonic Anhydrase
Mitophagy
Bcr-Abl
Reactive Oxygen Species
IGF-1R
mTOR
ATPase
Histone Methyltransferase
Virus Protease
MRP
IL Receptor
PGE Synthase
Trk receptor
c-RET
HIV Protease
Antifungal
RAAS
TOPK
Wnt/beta-catenin
Serine/threonin kinase
Caspase
MAO
Glucocorticoid Receptor
CaMK
DNA/RNA Synthesis
P-gp
SARS-CoV
ASK
CGRP Receptor
SGK
Thrombin
NOS
Transferase
HCV Protease
Dehydrogenase
LTR
Na+/Ca2+ Exchanger
NADPH
Glutathione Peroxidase
Phosphatase
ABC
HBV
Topoisomerase
Myosin
Mitochondrial Metabolism
JAK
Influenza Virus
FGFR
Syk
Estrogen/progestogen Receptor
PI3K
Adenosine Receptor
GTPase
Estrogen Receptor/ERR
Tyrosine Kinases
Serine Protease
AAK1 (AP2 associated kinase 1)
BTK
Chk
Epigenetic Reader Domain
DNA
Interleukin
TGF-beta/Smad
Acyltransferase
Antiviral
IκB/IKK
STAT
c-Fms
KLF
FAK
Proteasome
Proton pump
Transaminase
c-Met/HGFR
Antioxidant
IFNAR
DYRK
Lipase
Progesterone Receptor
GNRH Receptor
Pim
Leukotriene Receptor
CSF-1R
LDL
GlyT
ROS
DNA Alkylation
HSV
CCR
Epoxide Hydrolase
ACK
Androgen Receptor
Beta-Secretase
AChE
TLR
STING
LRRK2
Nrf2
ALK
GST
HDAC
AMPK
Hydroxylase
Gap Junction Protein
DNA Methyltransferase
IRAK
HMG-CoA Reductase
Protease-activated Receptor
AhR
PD-1/PD-L1
NO Synthase
Melanin-concentrating Hormone Receptor (MCHR)
Apelin receptor
Adenylyl cyclase
PROTACs
Taste receptor
Monocarboxylate transporter
Integrin
MyD88
Amino Acids and Derivatives
LPL Receptor
Reductase
Arrestin
RAR/RXR 
Tie-2
Melatonin Receptor
c-Myc
N-Acetylglucosaminyltransferase
CaSR
PARP
Antifolate
Cysteine Protease
LIM Kinase
PYK2
Aryl Hydrocarbon Receptor
Annexin A
FLAP
RIP kinase
UGT
PAFR
Gamma-secretase
GRK
MT Receptor
Glucagon Receptor
Na-K-Cl cotransporter
Antifection
Monoamine Transporter
Anion Exchanger
PROTAC Linker
BCL
PAK
Vasopressin Receptor
OX Receptor
MMP
cAMP
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
HSP
MRGPR
Free radical scavengers
Ephrin Receptor
transporter
GluCls
HuR
MELK
Hippo pathway
Beta Amyloid
GPX
Retinoid Receptor
RXFP receptor
DAPK
Platelet aggregation
NADPH-oxidase
BMI-1
NOD
cholecystokinin
Tyrosinase
NOD-like Receptor (NLR)
CFTR
Imidazoline Receptor
S1P Receptor
Kinesin

Keywords