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Antidiabetic agent 5 (compound S1) 是一种能够有效抑制α-葡萄糖苷酶 (α-glucosidase) 及 α-淀粉酶 (α-amylase) 的化合物,其 IC50 值分别为3.91 μM 和8.89 μM。此外,该化合物亦能有效降低血糖水平,显示出其对治疗 II 型糖尿病的潜在应用价值。
Antidiabetic agent 5 (compound S1) 是一种能够有效抑制α-葡萄糖苷酶 (α-glucosidase) 及 α-淀粉酶 (α-amylase) 的化合物,其 IC50 值分别为3.91 μM 和8.89 μM。此外,该化合物亦能有效降低血糖水平,显示出其对治疗 II 型糖尿病的潜在应用价值。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Compound S1 (antidiabetic agent 5) is an antidiabetic agent that effectively inhibits the enzymes α-glucosidase and α-amylase, demonstrating IC50 values of 3.91 µM and 8.89 µM, respectively. It reduces sugar levels and holds potential for type-II diabetes research [1]. |
体内活性 | The antidiabetic agent 5 (3.9, 7.8 mg/kg) effectively lowers blood glucose levels in diabetic BALB/c mice (26-33 g) [1]. Administration at 3.9 and 7.8 mg/kg resulted in reduced blood sugar levels (110–115 mg/dL), increased insulin levels (25–30 μM/L), as well as decreased cholesterol (85 mg/dL) and creatinine (0.6 mg/dL) levels [1]. |
分子量 | 357.38 |
分子式 | C17H15N3O4S |
CAS No. | 2152667-21-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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