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Autophagyinducer 5 (compound 21o) 作为一种有效的MCF-7抑制剂(IC50: 2 μM),具备成为潜在乳腺癌疗法的潜力。该化合物通过激活ROS/JNK信号通路来诱导细胞自噬,通过增加ROS生成和JNK磷酸化,最终发挥其细胞毒性作用。
Autophagyinducer 5 (compound 21o) 作为一种有效的MCF-7抑制剂(IC50: 2 μM),具备成为潜在乳腺癌疗法的潜力。该化合物通过激活ROS/JNK信号通路来诱导细胞自噬,通过增加ROS生成和JNK磷酸化,最终发挥其细胞毒性作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Autophagyinducer 5 (compound 21o) serves as a potent inhibitor of MCF-7 (IC50: 2 μM), making it a potential candidate for breast cancer therapy. It induces autophagy by activating the ROS/JNK signaling pathway, which increases ROS production and JNK phosphorylation, ultimately exerting cytotoxic effects. |
分子量 | 648.88 |
分子式 | C41H52N4O3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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