Koshidacin B, a cyclic tetrapeptide, exhibits potent antiplasmodial activity, evidenced by its ability to inhibit Plasmodium falciparum strains FCR3 and K1 with IC50 values of 0.89 μM and 0.83 μM, respectively. It has been shown to effectively suppress malaria parasites in vivo and has potential applications in parasitic infection research [1].

Koshidacin B（72小时）对氯喹敏感株P. falciparum FCR3和氯喹抗性株P. falciparum K1展现出抗疟作用，其半抑制浓度（IC 50）分别为0.89 μM和0.83 μM [1]。

Koshidacin B（7天）对人类MRC-5细胞显示出细胞毒性，IC 50值为14.7 μM [1]。

Koshidacin B（30 mg/kg；i.p.；每日一次，连续4天）展现了体内抗疟原虫效果[1]。