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1925

抑制剂 & 化合物

435

天然产物

26

化合物库

819

重组蛋白

21

同位素标记化合物

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Cat. No.	Product Name
L6700	抗癌天然产物库		1772 compounds
	1772 种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS 和HCS。
L2152	靶向治疗药物库		119 compounds
	119 个肿瘤靶向治疗药物，可以用于高通量和高内涵筛选；
L2130	抗癌细胞代谢库		1268 compounds
	1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
L2100	抗癌化合物库		7234 compounds
	7234 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2160	抗癌活性化合物库		3188 compounds
	3188 种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
L2200	酪氨酸激酶分子库		1016 compounds
	1016 种酪氨酸激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L2521	糖酵解化合物库		555 compounds
	555 种糖酵解相关的活性化合物，可用于高通量和高内涵筛选
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；
L2150	抗癌药物库		3080 compounds
	3080 个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；
L4800	血管生成库		1353 compounds
	1353 个高潜力的抑制或促进血管生成的小分子集合，可用于药物靶点开发、血管生成机理研究的高通量筛选，高内涵筛选；
L2140	癌细胞分化化合物库		406 compounds
	406 个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2180	抗肿瘤库Plus		1468 compounds
	1468 种抗肿瘤相关、结构新颖的化合物；
L2170	肿瘤免疫治疗小分子化合物库		449 compounds
	449 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；
L3700	JAK-STAT 化合物库		252 compounds
	252 个 JAK/STAT 靶点相关的小分子化合物的独特集合，用于高通量、高内涵筛选；
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L2500	人内源代谢化合物库		499 compounds
	499 种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选；
L2501	人内源代谢化合物库 Plus		1283 compounds
	1283种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L1300	PI3K/Akt/mTOR 化合物库		420 compounds
	420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合，用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选；
L4700	免疫/炎症分子化合物库		4720 compounds
	4720 种具有抗炎症活性的化合物的特有集合，可用于高通量筛选和高内涵筛选；
L6120	黄酮类天然产物库		514 compounds
	514 种黄酮类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L2520	糖代谢化合物库		702 compounds
	702 种糖代谢相关的化合物，可用于高通量和高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L8500	HIF-1化合物库		1336 compounds
	1336 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；
L6750	活血化瘀中药单体库		580 compounds
	580种来源于常见活血化瘀中药的单体化合物，是药物开发、药理研究等领域的有效工具。
L2196	抗卵巢癌化合物库		1867 compounds
	1867 种与卵巢癌相关的化合物，可以用于抗卵巢癌药物研发和药理研究
L6400	海洋天然产物库		144 compounds
	144 种海洋来源的单体化合物，是药物开发、药理研究等领域的有力工具；

化合物库

抗癌天然产物库

Cat.No: L6700

Compounds: 1772

靶向治疗药物库

Cat.No: L2152

Compounds: 119

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1268

抗癌化合物库

Cat.No: L2100

Compounds: 7234

抗癌活性化合物库

Cat.No: L2160

Compounds: 3188

酪氨酸激酶分子库

Cat.No: L2200

Compounds: 1016

糖酵解化合物库

Cat.No: L2521

Compounds: 555

核苷类化合物库

Cat.No: L1720

Compounds: 334

抗癌药物库

Cat.No: L2150

Compounds: 3080

血管生成库

Cat.No: L4800

Compounds: 1353

癌细胞分化化合物库

Cat.No: L2140

Compounds: 406

抗肿瘤库Plus

Cat.No: L2180

Compounds: 1468

肿瘤免疫治疗小分子化合物库

Cat.No: L2170

Compounds: 449

JAK-STAT 化合物库

Cat.No: L3700

Compounds: 252

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

人内源代谢化合物库

Cat.No: L2500

Compounds: 499

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1283

PI3K/Akt/mTOR 化合物库

Cat.No: L1300

Compounds: 420

免疫/炎症分子化合物库

Cat.No: L4700

Compounds: 4720

黄酮类天然产物库

Cat.No: L6120

Compounds: 514

糖代谢化合物库

Cat.No: L2520

Compounds: 702

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

HIF-1化合物库

Cat.No: L8500

Compounds: 1336

活血化瘀中药单体库

Cat.No: L6750

Compounds: 580

抗卵巢癌化合物库

Cat.No: L2196

Compounds: 1867

海洋天然产物库

Cat.No: L6400

Compounds: 144

Cat. No.	Product Name	Target	Signaling Pathways
TP2281	p53 tumor suppressor fragment	Others	Others
	p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where i
T76371	Tumor targeted pro-apoptotic peptide
	Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) 为抗肿瘤肽，具有破坏线粒体膜和促进细胞凋亡功能，展现小鼠的抗癌活性。
TP2299	tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]	Others	Others
	Tumor protein p53 binding protein (53BP1) has been identified in a yeast two-hybrid screen as a protein that interacts with the central DNA–binding domain of p532. Similar to breast cancer susceptibility gene 13, 4 (BRCA1; 53BP1 enhances p53-dependent tra
TP1472	Tyroserleutide	Others	Others
	Tyroserleutide 是一种可从猪脾脏的降解产物中分离得到的小分子三肽，在体内外均对肿瘤生长具有抑制作用。
T8469	LQZ-7I	Survivin	Apoptosis
	LQZ-7I 能口服有效地抑制异种移植肿瘤生长并诱导肿瘤中生存素的损失。它是一种靶向生存素的抑制剂，抑制生存素二聚化。
T8710	MSAB	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	MSAB 是一种Wnt/β-catenin 信号传导的选择性抑制剂。它能够与 β-catenin 结合，诱导其降解，并能够下调 Wnt/β-catenin 靶基因。它对 Wnt 依赖性癌细胞表现出有效的抗肿瘤特性。
T21408	DM1-SMe DM1-SSMe	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	DM1-SMe (DM1-SSMe) 是美登木素微管的有效抑制剂。 DM1-SMe 的效力是母体药物美登素的 3 至 10 倍，在一组人类肿瘤细胞系中，DM1-SMe 的 IC50 为 0.003 至 0.01 nM。
T4319	Hispidol (Z)-Hispidol	TNF	Apoptosis
	Hispidol ((Z)-Hispidol) 是一种炎症性肠病的潜在治疗剂，可抑制 TNF-α 诱导的单核细胞与结肠上皮细胞的粘附，IC50 为 0.50 μM。
T2430	HPOB	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	HPOB 是一种高选择性HDAC6抑制剂，IC50为 56 nM，其选择性是其他 HDAC 的 30 倍以上。它提高 DNA 损伤抗癌药物在转化细胞中的有效性。
T6540	Ibuprofen Lysine 布洛芬赖氨酸盐,Neoprofen	COX	Immunology/Inflammation; Neuroscience
	Ibuprofen Lysine (Neoprofen) 是一种非甾体抗炎药。
T0855	(R)-Naproxen	COX	Immunology/Inflammation; Neuroscience
	(R)-Naproxen 是一种抗炎剂，具有解热和镇痛作用。酸及其钠盐都用于治疗急性痛风或痛经、肌肉骨骼疾病、类风湿性关节炎和其他风湿病。
T7969	Dipyrithione	Others	Others
	Dipyrithione 似乎具有新的细胞毒性和强大的广谱抗肿瘤活性。
T10268	AGX51	Others	Others
	AGX51 是 DNA 结合蛋白抑制剂 (ID) 的拮抗剂。 AGX51 治疗导致泛 Id 降解、细胞周期停滞和细胞死亡。
T9127	MYLS22	Others	Others
	MYLS22 是视神经萎缩 1 的选择性抑制剂。它通过影响 NFkB 活性和血管生成基因表达抑制血管生成，靶向作用于内皮细胞 OPA1 ，减少肿瘤的生长。
TP1466	Z-YVAD-FMK	Caspase	Apoptosis; Proteases/Proteasome
	Z-YVAD-FMK 是一种不可逆的 caspase-1 抑制剂，具有抗炎和抗肿瘤活性。
T7614	Eniluracil GW776C85,5-Ethynyluracil	Others	Others
	Eniluracil (GW776C85) 是不可逆的二氢嘧啶脱氢酶(DPD)抑制剂，是一种尿嘧啶类似物，能够使 5-FU 的口服生物利用度提高到 100%，促进均匀吸收和可预测的毒性。
T14848	C 87	Others; TNF	Apoptosis; Others
	C 87 是一种小分子 TNF-α 抑制剂。 C 87 直接与 TNFα 结合，有效抑制 TNF-α 诱导的细胞毒性 (IC50 = 8.73 μM)，并有效阻断 TNF-α 触发的信号传导活动。
T1394	Ibuprofen Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil	COX	Immunology/Inflammation; Neuroscience
	Ibuprofen (Advil) 是一种丙酸衍生物和非甾体抗炎药 (NSAID)，具有抗炎、镇痛和解热作用。它是COX-1和COX-2的抑制剂，IC50值分别为 13 和 370 μM，导致前列腺素和血栓素前体的形成减少。
T17208	USL311	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	USL311 是选择性 CXCR4拮抗剂，可防止基质细胞衍生因子 1（SDF-1 或 CXCL12）与 CXCR4 结合。它抑制 CXCR4 活化并减少表达 CXCR4 的肿瘤细胞的增殖和迁移，具有抗肿瘤活性。
T8395	Nomegestrol acetate	Others; Progesterone Receptor	Others
	Nomegestrol acetate 是一种孕酮受体的完全激动剂，是一种高选择性孕激素。
T9050	AG-270	Others; Methionine Adenosyltransferase (MAT)	Chromatin/Epigenetic; Others
	AG-270 是一种可逆的、非竞争性的、具有口服活性的MAT2A 变构抑制剂(IC50:14 nM)。
T9271	RAD51-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	RAD51-IN-1 是 B02 的衍生物，是一种RAD51的有效抑制剂，可研究癌症。
T6393	ARQ 621	Kinesin	Cytoskeletal Signaling
	ARQ 621 是一种变构和选择性 Eg5 有丝分裂运动蛋白抑制剂，具有抗肿瘤活性。
T39233	SIRT7 inhibitor 97491	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	SIRT7 inhibitor 97491 是SIRT7的有效抑制剂，IC50为 325 nM。SIRT7 inhibitor 97491以剂量依赖性的方式降低 SIRT7 去乙酰化酶活性。它通过在 K373/382 处进行乙酰化来提高 p53 的稳定性，从而防止肿瘤进展。它通过 caspase 途径促进凋亡。
T9918	Daratumumab 达妥木单抗	Others; ADC Antibody	Antibody-drug Conjugate/ADC Related; Others
	Daratumumab 是一种首创的特异性抗CD38单克隆抗体。它损伤了 MM 细胞的粘附，从而增加了 MM 对蛋白酶体抑制的敏感性。它具有抗多发性骨髓瘤(MM) 的作用。
T10255	AES-135	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	AES-135 是一种基于羟肟酸的泛HDAC 抑制剂，抑制 HDAC3、HDAC6和 HDAC11，IC50为 654、190 和 636 nM，具有抗肿瘤活性。
T39695	ARD-2128	Androgen Receptor; PROTACs	Endocrinology/Hormones; PROTAC
	ARD-2128 是高效的雄激素受体降解剂 PROTAC。它可有效降低雄激素受体蛋白并抑制肿瘤组织中雄激素受体调节的基因，在没有毒性迹象的情况下抑制肿瘤生长。它有用于前列腺癌研究的价值。
T41277	PACMA 31	Others	Others
	PACMA 31 是一种不可逆的共价蛋白二硫键异构酶 (PDI) 抑制剂，IC50 为 10 μM。 PACMA 31 显着抑制卵巢肿瘤生长并表现出肿瘤靶向能力。
T5484	GSK467	Histone Demethylase; Histone Methyltransferase	Chromatin/Epigenetic
	GSK467 是一种有效的、选择性的 KDM5 (JARID1) 抑制剂，Ki 值为10 nM。
T9921	Infliximab	TNF	Apoptosis
	Infliximab 是一种与 TNF-α特异性结合的嵌合单克隆 IgG1 抗体，可阻止 TNF-α与 TNFR1和 TNFR2 的相互作用，用于治疗克罗恩病和类风湿性关节炎。
T8843	APS6-45	MAPK; Ras	GPCR/G Protein; MAPK
	APS6-45 是一种可口服的肿瘤校准抑制剂，可抑制 RAS/MAPK 信号传导并表现出抗肿瘤活性。
T6003	GSK1904529A GSK 4529	Apoptosis; Raf; VEGFR; IGF-1R; Syk	Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
	GSK1904529A (GSK 4529) 是一种选择性，具有口服活性和 ATP 竞争性的胰岛素样生长因子 1 受体和胰岛素受体抑制剂，IC50值分别为 27 和 25 nM。它具有抗肿瘤活性。
T13167	TLR7/8 agonist 3	TLR	Immunology/Inflammation
	TLR7/8 agonist 3 是TLR7/8激动剂。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T9622	MF-766	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	MF-766 是高效的、具有口服活性的EP4选择性拮抗剂，Ki 为 0.23 nM。它在功能检测中表现为一种完整的拮抗剂，其 IC50为 1.4 nM (在 10% HS 存在时变成 1.8 nM)。它具有用于癌症和炎症疾病研究的价值。
T4288	hVEGF-IN-1	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	hVEGF-IN-1 是一种喹唑啉衍生物，可以特异性结合内部核糖体进入位点 A 中富含 G 的序列，并会使 G-四链体结构不稳定。在 SPR 实验中，它与 IRES-A (WT) 结合的Kd 值为 0.928 μM。它能够抑制VEGF-A 蛋白表达，阻止肿瘤细胞迁移，抑制肿瘤生长。
T3072	XL019	Apoptosis; FLT; JAK; PDGFR	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	XL019 是一种具有口服活性的选择性JAK2抑制剂。它对JAK2的选择性是 100 多种丝氨酸/苏氨酸和酪氨酸激酶的 50 倍以上。它对 JAK2 V617F 和野生型 JAK2 细胞中 STAT3 和 STAT5 磷酸化有抑制作用。
T8956	BC-1258 BC-1258	Apoptosis	Apoptosis
	BC-1258 是一种 F-box/LRR-重复蛋白 2激活剂，可诱导致瘤细胞凋亡，并显著抑制小鼠的肿瘤形成，还可以稳定和上调 FBXL2 水平。
T10425	AZ084	CCR	Immunology/Inflammation; Microbiology/Virology
	AZ084 是可口服的选择性 CCR8变构拮抗剂，其Ki 值为 0.9 nM，可研究哮喘。
T22414	RBN012759	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	RBN012759 是选择性和具有口服活性的 PARP14抑制剂，IC50值小于3 nM，可降低促肿瘤巨噬细胞功能并在肿瘤外植体中引发炎症反应，比对 monoPARPs 的选择性高 300 倍，比对 polyPARPs 的选择性高 1000 倍。
T8310	MMP-9-IN-1	MMP	Proteases/Proteasome
	MMP-9-IN-1 是特异性的基质金属蛋白酶-9 抑制剂，选择性靶向 MMP-9 的血红素域，对其他 MMP 无影响。
T8668	HM03	HSP	Cytoskeletal Signaling; Metabolism
	HM03 是一种有效的选择性 HSPA5 抑制剂，具有抗癌活性。
T22428	Sodium Glucoheptonate Sodium glucoheptonate,葡萄醣庚酸钠	Others	Others
	Sodium Glucoheptonate 可用作 Tc-99m 放射性标记的试剂盒，也可用于清洗金属、丝光、脱漆和铝蚀刻。其中Tc-99m glucoheptonate 是一种肾脏和脑部成像剂，可用于检测脑肿瘤。
T3105	PFK-158	Apoptosis; Glucokinase; Autophagy	Apoptosis; Autophagy; Metabolism
	PFK158 是一种选择性的PFKFB3抑制剂，IC50值为 137 nM。它可减少癌细胞中葡萄糖的摄取，ATP 的产生，乳酸的释放，并诱导细胞凋亡和自噬。它还可以增强 Colistin 对细菌的抵抗力，具有广泛的抗肿瘤活性。
T9470	HPK1-IN-7	MAPK	MAPK
	HPK1-IN-7 是一种口服有活性的、有效的HPK1(造血祖细胞激酶1, MAP4K1) 抑制剂，其IC50值为2.6 nM，具有强大的家族及激酶组选择性。它对 IRAK4 (59 nM) 和 GLK (140 nM) 具有选择性。当它与抗 PD1联合使用时，对 MC38 同基因肿瘤模型表现出极大的疗效。
T11096	DRI-C21045	NF-κB	NF-κB
	DRI-C21045 是一种有效的 CD40-CD40L 协同刺激蛋白-蛋白质相互作用的选择性抑制剂，IC50 为 0.17 μM。它显示对 CD40L 诱导的 NF-κB 活化和 B 细胞增殖的浓度依赖性抑制，IC50分别为 17.1 μM 和 4.5 μM。
T2065	Bioymifi DR5 Activator	Apoptosis; TNF	Apoptosis
	Bioymifi (DR5 Activator) 是一种 TRAIL 受体DR5激活剂，与DR5的胞外结构域结合，Kd 为 1.2 μM，它可诱导 DR5 聚集，导致细胞凋亡。
T9303	MRTX1133	Ras	GPCR/G Protein; MAPK
	MRTX1133 是一种 KRAS G12D 抑制剂 (KD=0.2 pM)，具有强效性、选择性和非共价性。MRTX1133 对 KRAS G12D 突变的肿瘤具有抑制活性，而对 KRAS 野生型肿瘤无抑制活性。
T21981	Phthalazinone pyrazole	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Phthalazinone pyrazole 是强效、选择性和口服生物可利用的 Aurora-A 激酶抑制剂，IC50值为 0.031 μM。它抑制人胚胎干细胞向肝细胞样细胞分化过程中的上皮间质转化。它还可阻止有丝分裂并随后通过增殖细胞的凋亡抑制肿瘤生长。
T11399	Giredestrant GDC-9545	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Giredestrant (GDC-9545) 是一种口服有效的、选择性的、非甾体的雌激素受体 (ER) 拮抗剂，具有抗肿瘤作用。它可以在 ER 配体结合域内与雌二醇 (Estradiol) 竞争结合并诱导构象变化。

化合物

p53 tumor suppressor fragment

Cat.No: TP2281

Target: Others

Tumor targeted pro-apoptotic peptide

Cat.No: T76371

tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]

Cat.No: TP2299

Target: Others

Cat.No: TP1472

Target: Others

Cat.No: T8469

Target: Survivin

Cat.No: T8710

Target: Wnt/beta-catenin

Cat.No: T21408

Synonym: DM1-SSMe

Target: Microtubule Associated, ADC Cytotoxin

Cat.No: T4319

Synonym: (Z)-Hispidol

Target: TNF

Cat.No: T2430

Target: Apoptosis, HDAC

Ibuprofen Lysine

Cat.No: T6540

Synonym: 布洛芬赖氨酸盐,Neoprofen

Target: COX

Cat.No: T0855

Target: COX

Cat.No: T7969

Target: Others

Cat.No: T10268

Target: Others

Cat.No: T9127

Target: Others

Cat.No: TP1466

Target: Caspase

Cat.No: T7614

Synonym: GW776C85,5-Ethynyluracil

Target: Others

Cat.No: T14848

Target: Others, TNF

Cat.No: T1394

Synonym: Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil

Target: COX

Cat.No: T17208

Target: CXCR

Nomegestrol acetate

Cat.No: T8395

Target: Others, Progesterone Receptor

Cat.No: T9050

Target: Others, Methionine Adenosyltransferase (MAT)

Cat.No: T9271

Target: DNA/RNA Synthesis

Cat.No: T6393

Target: Kinesin

SIRT7 inhibitor 97491

Cat.No: T39233

Target: Sirtuin

Cat.No: T9918

Synonym: 达妥木单抗

Target: Others, ADC Antibody

Cat.No: T10255

Target: HDAC

Cat.No: T39695

Target: Androgen Receptor, PROTACs

Cat.No: T41277

Target: Others

Cat.No: T5484

Target: Histone Demethylase, Histone Methyltransferase

Cat.No: T9921

Target: TNF

Cat.No: T8843

Target: MAPK, Ras

Cat.No: T6003

Synonym: GSK 4529

Target: Apoptosis, Raf, VEGFR, IGF-1R, Syk

TLR7/8 agonist 3

Cat.No: T13167

Target: TLR

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

Cat.No: T9622

Target: Prostaglandin Receptor

Cat.No: T4288

Target: VEGFR

Cat.No: T3072

Target: Apoptosis, FLT, JAK, PDGFR

Cat.No: T8956

Synonym: BC-1258

Target: Apoptosis

Cat.No: T10425

Target: CCR

Cat.No: T22414

Target: PARP

Cat.No: T8310

Target: MMP

Cat.No: T8668

Target: HSP

Sodium Glucoheptonate

Cat.No: T22428

Synonym: Sodium glucoheptonate,葡萄醣庚酸钠

Target: Others

Cat.No: T3105

Target: Apoptosis, Glucokinase, Autophagy

Cat.No: T9470

Target: MAPK

Cat.No: T11096

Target: NF-κB

Cat.No: T2065

Synonym: DR5 Activator

Target: Apoptosis, TNF

Cat.No: T9303

Target: Ras

Phthalazinone pyrazole

Cat.No: T21981

Target: Aurora Kinase

Cat.No: T11399

Synonym: GDC-9545

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T4035	Khasianine	Others	Others
	Khasianine 是一种从茄属植物Solanum Nigrum L 中提取的甾体糖生物碱，具有抗肿瘤作用。
T6S2099	Geraniin	Antioxidant; TNF	Apoptosis; oxidation-reduction
	Geraniin 是一种肿瘤坏死因子α释放抑制剂，其IC50值为 43 μM，具有抗肿瘤、抗炎和抗高血糖活性。
TN5173	Trichorabdal A	Antifection	Microbiology/Virology
	Trichorabdal A 是一种二萜化合物，分离自 Rabdosia trichocarpa，抗肿瘤作用强大。
T6S0630	Hypaconitine	P450; TNF	Apoptosis; Metabolism
	Hypaconitine 是从乌头属种分离的一种高毒性成分，可研究风湿病。
T4S1849	Tubeimoside III	Others	Others
	Tubeimoside III 是一种具有抗炎和抗肿瘤活性的三萜皂苷，在体内具急性毒性。
T10021	1-Methylxanthine	Endogenous Metabolite	Metabolism
	1-Methylxanthine 是咖啡因衍生物，是咖啡因和茶碱 (1,3-二甲基黄嘌呤，TP) 在人体尿代谢产物，能够提高肿瘤细胞的放射敏感性。
T37101	1-Hydroxyanthraquinone	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	1-Hydroxyanthraquinone 是口服有效的天然产物，来源于植物 Tabebuia avellanedae，显示出致癌活性。
TN2182	Sarracenin 脱水莫诺苷元,金银花	Others	Others
	Sarracenin 是一种的环烯醚萜，分离自鸢尾草的根和根茎中。它对肿瘤细胞显示出细胞毒作用。
T9135	Epirosmanol	Others	Others
	Epirosmanol 是含有内酯部分的二萜类化合物。 Epirosmanol 是一种极弱碱性（基本中性）的化合物（基于其 pKa）。
T13509	4-Vinylphenol	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	4-Vinylphenol 是酒中乳酸菌对香豆酸和阿魏酸的代谢产物，在白花蛇舌草中发现。 4-Vinylphenol 在体内诱导细胞凋亡。
T4S0217	HOMOPLANTAGININ	TNF; NF-κB	Apoptosis; NF-κB
	Homoplantaginin 是来自中药荔枝草的一种类黄酮，具有抗炎和抗氧化活性。
T37512	cis-4-Hydroxy-L-proline	Endogenous Metabolite	Metabolism
	cis-4-Hydroxy-L-proline 是脯氨酸的一种类似物，抑制胶原蛋白的产生。它通过阻止三层螺旋胶原在细胞层上的沉积从而抑制成纤维细胞的生长。它还可抑制原发性N-亚硝基甲基脲诱导的大鼠乳腺肿瘤的生长。
T5S1982	Periplocin Periplocoside,杠柳毒苷	Apoptosis; Others	Apoptosis; Others
	Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径，具有促进伤口愈合的潜力。
T6S0627	Mesaconitine 新乌碱,新乌头碱；中乌头碱	TNF	Apoptosis
	Mesaconitine 是乌头属植物的一种主要活性成分，通过循环 AMP 和刺激中枢 β-肾上腺素能系统具有镇痛活性，还有抗炎活性。
T2879	Fisetin 漆黄素,非瑟酮	TNF; Sirtuin; PPAR	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Fisetin 是在许多水果和蔬菜中发现的一种天然黄酮醇，有抗氧化、抗癌和神经保护作用。
T3314	Perillyl alcohol Isocarveol,Perilla alcohol,紫苏醇	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	Perillyl alcohol (Isocarveol) 是一种单萜，可在不影响正常细胞的情况下诱导肿瘤细胞凋亡。
T6S1597	Mulberroside A 桑皮苷 A,桑皮苷A	TNF; Tyrosinase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Mulberroside A 是桑中的一种主要活性成分，可降低TNF-α、IL-1β和IL-6的表达，抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。它抑制蘑菇酪氨酸酶，具有抗炎和抗细胞凋亡作用。
T5808	(-)-Oxypeucedanin hydrate 水合氧化前胡素,OXYPEUCEDANIN HYDRATE	Others	Others
	(-)-Oxypeucedanin hydrate 是一种呋喃香豆素衍生物，分离自Ducrosia anethifolia 中。
T2217	Cephalomannine Baccatin III,三尖杉宁碱	Microtubule Associated	Cytoskeletal Signaling
	Cephalomannine (Baccatin III) 是一种从云南红豆杉中提取的紫杉醇衍生物，具有抗肿瘤活性，可用于癌症研究。
T8678	Naphthazarin 萘茜,5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) 是来自毛紫草的一种天然产物，通过氧化应激、线粒体凋亡诱导因子的激活、微管的解聚、干扰溶酶体功能和 p53 依赖性 p21 激活，可触发细胞凋亡并具有抗肿瘤作用。
TN6490	Regaloside C	Others	Others
	Regaloside C 是一种从百合属的中分离出来的甘油葡糖苷，具有抗炎作用。
TN2132	Quinizarin 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌	Others; DNA/RNA Synthesis; Antifungal	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Quinizarin (1,4-Dihydroxyanthraquinone) 是一种杀菌剂和杀虫剂，可抑制肿瘤细胞生长。
T4S0227	Sinensetin Pedalitin permethyl ether,甜橙素	TNF; PGE Synthase	Apoptosis; Immunology/Inflammation
	Sinensetin (Pedalitin permethyl ether) 是从水果中发现的一种甲基化黄酮，有很强的抗血管和抗炎症的能力。
T4S2126	Ginkgetin 银杏双黄酮,银杏素	Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
	Ginkgetin 是从银杏叶中分离得到的一种双黄酮，具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂，IC50值为 5.92 μM。
T1032	Erythromycin 红霉素,E-Mycin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Erythromycin (E-Mycin) 是由放线菌产生的大环内酯类抗生素。它结合细菌的 50S 核糖体亚基，通过阻断转肽和易位反应来抑制 RNA 依赖性蛋白的合成。
TN1413	Atranorin 荔枝素，巴美灵,荔枝素	Endogenous Metabolite; NO Synthase; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
	Atranorin 是地衣的次生代谢产物，具有显着的抗伤害、抗炎和氧化还原活性，对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
TN1721	Gypenoside L	ERK; p38 MAPK; Calcium Channel; NF-κB; ROS	Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Metabolism; NF-κB
	Gypenoside L 是存在于绞股蓝中的一种皂苷，可增加 SA-β-半乳糖苷酶活性，促进衰老相关分泌细胞因子的产生。它还可以激活p38和ERK MAPK 通路和NF-κB 通路以诱导衰老，具有抗肿瘤和抗炎活性。
T32291	Jineol NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081	Others	Others
	Jineol (NSC-694081) 是一种来自蜈蚣 Scolopendra subspinipes 的喹啉生物碱。Jineol 在体外对人类肿瘤细胞系的生长具有细胞毒活性。
T3893	Forsythoside B 连翘酯苷 B,连翘脂苷B	TNF; NF-κB	Apoptosis; NF-κB
	Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
T3912	Saikosaponin B1 柴胡皂苷B1,柴胡皂苷 B1	Others	Others
	Saikosaponin B1 是柴胡的生物活性成分，具有抗癌作用。它能够靶向SMO 抑制 Hedgehog 通路，显著抑制髓母细胞瘤模型中的肿瘤生长。
T13818	Phytohemagglutinin PHA-M,植物血球凝集素,PHA,植物血凝素	Apoptosis	Apoptosis
	Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素，聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂，能够刺激人单核白细胞，可诱导 ChAT mRNA 表达，增强 ACh 合成。
TN4761	Phellamurin	P-gp	Membrane transporter/Ion channel; Neuroscience
	Phellamurin 是一种来自黄檗叶的黄酮糖苷，可诱导细胞凋亡，具有抗肿瘤活性。它抑制肠道 P-糖蛋白，还抑制凤蝶的产卵。
T2S0731	Trilobatin 三叶苷,三叶甙,P-Phlorizin	Amylase	Metabolism
	Trilobatin (P-Phlorizin) 是源自Lithocarpus polystachyusRehd 的甜味剂，是一种HIV-1抑制剂，靶向 Gp41 包膜蛋白，具有神经保护作用。它还是SGLT1/2抑制剂，可选择性诱导人肝母细胞瘤细胞增殖。
T3S0737	Flavokawain A 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A	Apoptosis; p38 MAPK	Apoptosis; MAPK
	Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮，是一种抗癌试剂，具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡，有潜力用于膀胱癌的相关研究。
T4S1521	1,4-Dicaffeoylquinic acid 1,4-二咖啡酰奎宁酸,洋蓟素	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	1,4-Dicaffeoylquinic acid 是一种苯丙素类物质，从苍耳子中获得，可以减少 LPS 诱导的 TNF-α 的生成，具有抗炎活性。
T6S2140	β-Anhydroicaritin Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素	MMP; Others; TNF; Interleukin	Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome
	β-Anhydroicaritin 是从乳香提取的一种天然产物，具有重要的生物学和药理学作用，如抗骨质疏松症，雌激素调节和抗肿瘤特性。它改善牙周组织的降解，抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高，并显著降低 iNOS 蛋白的表达。
T21351	Maytansine NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine,美坦新	Microtubule Associated; Antibiotic	Cytoskeletal Signaling; Microbiology/Virology
	Maytansine (NSC-153858) 是从变叶美登木中分离的一种高效微管靶向天然产物，可诱导有丝分裂阻滞并在亚纳摩尔浓度杀死肿瘤细胞。
T3S1416	Decursin Decursinol angelate,前胡素,(+)-Decursin,紫花前胡素	Apoptosis; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	Decursin (Decursinol angelate) 是一种细胞毒性剂，是一种来自朝鲜当归根的有效蛋白激酶 C 激活剂。它通过 Hippo/YAP 信号通路抑制 HepG2 细胞的生长。它通过下调 CXCR7 表达来抑制胃癌中的肿瘤生长，迁移和侵袭。
T5S0106	Peimisine 贝母辛,Ebeiensine	RAAS; AChR	Endocrinology/Hormones; Neuroscience
	Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体，抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放，促进一氧化氮释放，可舒张气管平滑肌，有平喘作用。
T5S0018	Betulonic acid 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite; HSV	Microbiology/Virology
	Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物，具有抗肿瘤，抗炎，抗寄生虫和抗病毒的活性。
T2720	Ginsenoside Rc Panaxoside Rc,人参皂苷Rc,人参皂苷 Rc	Others; TNF; GABA Receptor; Interleukin	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; Others
	Ginsenoside Rc (Panaxoside Rc) 是人参中的一种人参皂苷，可抑制 TNF-α 和 IL-1β 的表达。它增强 GABA 受体 A 介导的离子通道电流。
T2S1200	Sinapine	Antioxidant; P-gp; AChE	Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
	Sinapine 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
T1511	Daunorubicin hydrochloride Daunomycin HCl,盐酸佐柔比星,盐酸柔红霉素,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin	Apoptosis; DNA/RNA Synthesis; Topoisomerase; Antibacterial; Antibiotic; Autophagy; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Daunorubicin hydrochloride (Rubidomycin hydrochloride) 是一种蒽环类氨基糖苷类化合物，一种拓扑异构酶 II (Topo II) 抑制剂。Daunorubicin hydrochloride 可以抑制 DNA 和 RNA 的合成，具有抗肿瘤活性。
T5S1882	Songorine 准葛尔乌头碱,Napellonine,Zongorine,Bullatine G	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	Songorine (Napellonine) 是从乌头属中分离出的一种二萜生物碱，具有抗癌、抗心律不齐和抗炎活性。它是大鼠脑中的GABAA 受体拮抗剂，有用于上皮性卵巢癌的研究潜力。
T7786	Tryptanthrin	DNA gyrase	DNA Damage/DNA Repair
	Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
T1181	Gefitinib ZD1839,吉非替尼	EGFR; Tyrosine Kinases; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Gefitinib (ZD1839) 是一种 EGFR 一代抑制剂，具有口服活性，抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
T3392	Sinapine thiocyanate	P-gp; AChE	Membrane transporter/Ion channel; Neuroscience
	Sinapine thiocyanate 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
T19720	Colcemid C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine	Microtubule Associated	Cytoskeletal Signaling
	Colcemid (NSC-3096) 是一种微管聚合抑制剂，可诱导细胞凋亡，可用于肿瘤和胚胎克隆的研究。
T4586	(Rac)-Arnebin 1 β,β-二甲基丙烯酰阿卡宁,beta, beta-dimethylacrylshikonin	Others	Others
	(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) 具有抗肿瘤作用，是β,β-Dimethylacrylalkannin 和 β,β-Dimethylacrylshikonin 的消旋体。β,β-Dimethylacrylalkannin 和 β,β-Dimethylacrylshikonin 是分离自紫草属植物中的萘醌类化合物。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
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天然产物

Cat.No: T4035

Target: Others

Cat.No: T6S2099

Target: Antioxidant, TNF

Cat.No: TN5173

Target: Antifection

Cat.No: T6S0630

Target: P450, TNF

Tubeimoside III

Cat.No: T4S1849

Target: Others

1-Methylxanthine

Cat.No: T10021

Target: Endogenous Metabolite

1-Hydroxyanthraquinone

Cat.No: T37101

Target: DNA/RNA Synthesis

Cat.No: TN2182

Synonym: 脱水莫诺苷元,金银花

Target: Others

Cat.No: T9135

Target: Others

Cat.No: T13509

Target: Apoptosis, Endogenous Metabolite

HOMOPLANTAGININ

Cat.No: T4S0217

Target: TNF, NF-κB

cis-4-Hydroxy-L-proline

Cat.No: T37512

Target: Endogenous Metabolite

Cat.No: T5S1982

Synonym: Periplocoside,杠柳毒苷

Target: Apoptosis, Others

Cat.No: T6S0627

Synonym: 新乌碱,新乌头碱；中乌头碱

Target: TNF

Cat.No: T2879

Synonym: 漆黄素,非瑟酮

Target: TNF, Sirtuin, PPAR

Perillyl alcohol

Cat.No: T3314

Synonym: Isocarveol,Perilla alcohol,紫苏醇

Target: Apoptosis, Endogenous Metabolite

Cat.No: T6S1597

Synonym: 桑皮苷 A,桑皮苷A

Target: TNF, Tyrosinase, Interleukin

(-)-Oxypeucedanin hydrate

Cat.No: T5808

Synonym: 水合氧化前胡素,OXYPEUCEDANIN HYDRATE

Target: Others

Cat.No: T2217

Synonym: Baccatin III,三尖杉宁碱

Target: Microtubule Associated

Cat.No: T8678

Synonym: 萘茜,5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Target: Apoptosis

Cat.No: TN6490

Target: Others

Cat.No: TN2132

Synonym: 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌

Target: Others, DNA/RNA Synthesis, Antifungal

Cat.No: T4S0227

Synonym: Pedalitin permethyl ether,甜橙素

Target: TNF, PGE Synthase

Cat.No: T4S2126

Synonym: 银杏双黄酮,银杏素

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Cat.No: T1032

Synonym: 红霉素,E-Mycin

Target: ribosome, Antibacterial, Antibiotic

Cat.No: TN1413

Synonym: 荔枝素，巴美灵,荔枝素

Target: Endogenous Metabolite, NO Synthase, Ras

Cat.No: TN1721

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Cat.No: T32291

Synonym: NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081

Target: Others

Cat.No: T3893

Synonym: 连翘酯苷 B,连翘脂苷B

Target: TNF, NF-κB

Saikosaponin B1

Cat.No: T3912

Synonym: 柴胡皂苷B1,柴胡皂苷 B1

Target: Others

Phytohemagglutinin

Cat.No: T13818

Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素

Target: Apoptosis

Cat.No: TN4761

Target: P-gp

Cat.No: T2S0731

Synonym: 三叶苷,三叶甙,P-Phlorizin

Target: Amylase

Cat.No: T3S0737

Synonym: 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A

Target: Apoptosis, p38 MAPK

1,4-Dicaffeoylquinic acid

Cat.No: T4S1521

Synonym: 1,4-二咖啡酰奎宁酸,洋蓟素

Target: HIV Protease

β-Anhydroicaritin

Cat.No: T6S2140

Synonym: Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素

Target: MMP, Others, TNF, Interleukin

Cat.No: T21351

Synonym: NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine,美坦新

Target: Microtubule Associated, Antibiotic

Cat.No: T3S1416

Synonym: Decursinol angelate,前胡素,(+)-Decursin,紫花前胡素

Target: Apoptosis, PKC

Cat.No: T5S0106

Synonym: 贝母辛,Ebeiensine

Target: RAAS, AChR

Cat.No: T5S0018

Synonym: 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Target: Parasite, HSV

Cat.No: T2720

Synonym: Panaxoside Rc,人参皂苷Rc,人参皂苷 Rc

Target: Others, TNF, GABA Receptor, Interleukin

Cat.No: T2S1200

Target: Antioxidant, P-gp, AChE

Daunorubicin hydrochloride

Cat.No: T1511

Synonym: Daunomycin HCl,盐酸佐柔比星,盐酸柔红霉素,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy, ADC Cytotoxin

Cat.No: T5S1882

Synonym: 准葛尔乌头碱,Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Cat.No: T7786

Target: DNA gyrase

Cat.No: T1181

Synonym: ZD1839,吉非替尼

Target: EGFR, Tyrosine Kinases, Autophagy

Sinapine thiocyanate

Cat.No: T3392

Target: P-gp, AChE

Cat.No: T19720

Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine

Target: Microtubule Associated

(Rac)-Arnebin 1

Cat.No: T4586

Synonym: β,β-二甲基丙烯酰阿卡宁,beta, beta-dimethylacrylshikonin

Target: Others

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02975	Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc) Wt1,Wilms tumor protein homolog	Mouse	E. coli
	Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.7 kDa and the accession number is P22561.
TMPH-02312	Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO) WT1,WT33,Wilms tumor protein	Human	E. coli
	Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may b...
TMPY-05153	TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His) tumor-associated calcium signal transducer 2	Cynomolgus,Rhesus	HEK293 Cells
	TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.7 kDa and the accession number is XP_001114599.1.
TMPY-03101	TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His) tumor necrosis factor receptor superfamily, member ...	Cynomolgus,Rhesus	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is XP_005544817.1&NP_001253134.1.
TMPY-01429	RELT/TNFRSF19L Protein, Human, Recombinant (His) TRLT,TNFRSF19L,RELT tumor necrosis factor receptor	Human	HEK293 Cells
	RELT/TNFRSF19L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is A0A024R5N3.
TMPY-03213	BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc) tumor necrosis factor receptor superfamily member 1...	Rhesus	HEK293 Cells
	BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is A0A2K5UD97.
TMPY-05504	4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated tumor necrosis factor receptor superfamily, member ...	Rhesus	HEK293 Cells
	4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is XP_005544945.1&NP_001253057.1.
TMPY-03645	BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc) tumor necrosis factor (ligand) superfamily, member ...	Cynomolgus	HEK293 Cells
	BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is F7H548.
TMPY-04289	CD30L Protein, Cynomolgus, Recombinant (His) tumor necrosis factor (ligand) superfamily, member ...	Cynomolgus	HEK293 Cells
	CD30L Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is G7P2F1.
TMPY-02202	TNF alpha Protein, Rat, Recombinant tumor necrosis factor,肿瘤坏死因子,TNF-α	Rat	E. coli
	TNF alpha Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P16599.
TMPY-04146	TNF alpha Protein, Human, Recombinant (hFc) DIF,TNFA,tumor necrosis factor,TNFSF2,TNF-α,TNF-alp...	Human	HEK293 Cells
	TNF alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is P01375.
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿...	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ...
TMPJ-00139	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) 4-1BBL,Tumor necrosis factor ligand superfamily mem...	Human	E. coli
	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16-20 KDa and the accession number is P41273.
TMPY-00705	CD30L Protein, Human, Recombinant (hFc) CD153,CD30L,tumor necrosis factor (ligand) superfam...	Human	HEK293 Cells
	CD30L Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P32971.
TMPH-02646	Erythroferrone Protein, Mouse, Recombinant (His) Erythroferrone,Myonectin,Erfe,Complement C1q tumor ...	Mouse	P. pastoris (Yeast)
	Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Erythroferrone Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted m...
TMPY-04645	TL1A/TNFSF15 Protein, Human, Recombinant (hFc) TL1,tumor necrosis factor (ligand) superfamily, mem...	Human	HEK293 Cells
	TL1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is A0A0U5JA19.
TMPY-05319	BCMA/TNFRSF17 Protein, Human, Recombinant (His) BCMA,TNFRSF13A,CD269,tumor necrosis factor receptor...	Human	HEK293 Cells
	BCMA/TNFRSF17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 7.3 kDa and the accession number is Q02223-1.
TMPY-00936	TNF alpha Protein, Human, Recombinant TNFA,TNFSF2,TNF-alpha,TNF-α,DIF,肿瘤坏死因子,tumor necros...	Human	E. coli
	TNF alpha Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P01375.
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor superfamily,...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-05594	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated CDw137,CD137,4-1BB,tumor necrosis factor receptor s...	Human	HEK293 Cells
	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 45.8 kDa and the accession number is Q07011.
TMPY-05568	BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated BCMA,TNFRSF13A,tumor necrosis factor receptor super...	Human	HEK293 Cells
	BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated is expressed in HEK293 mammalian cells with His and Fc tag. The accession number is NP_001183.2.
TMPY-04493	BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) tumor necrosis factor receptor superfamily member 1...	Human	HEK293 Cells
	BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 33.3 kDa and the accession number is Q02223-1.
TMPY-05376	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc) 4-1BB,tumor necrosis factor receptor superfamily, m...	Human	HEK293 Cells
	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is Q07011.
TMPY-00033	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) CD137L,4-1BB-L,tumor necrosis factor (ligand) super...	Human	HEK293 Cells
	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the accession number is A0A0U5J8I0.
TMPY-01743	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) 4-1BB,tumor necrosis factor receptor superfamily, m...	Human	HEK293 Cells
	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.8 kDa and the accession number is Q07011.
TMPY-02667	TROP-2 Protein, Mouse, Recombinant (His) Ly97,TROP2,tumor-associated calcium signal transduc...	Mouse	HEK293 Cells
	TROP-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is Q8BGV3.
TMPY-02726	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) RANKL,OPGL,Trance,OPG,tumor necrosis factor (ligand...	Mouse	HEK293 Cells
	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is AAC40113.1.
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His) AITR,GITR-D,tumor necrosis factor receptor superfam...	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) OPG,Tumor Necrosis Factor Receptor Superfamily Memb...	Human	HEK293 Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPY-01750	HVEM Protein, Human, Recombinant (His) HVEA,TR2,HVEM,ATAR,tumor necrosis factor receptor s...	Human	HEK293 Cells
	HVEM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is A0A024R052.
TMPY-01423	OX40/TNFRSF4 Protein, Human, Recombinant (His) tumor necrosis factor receptor superfamily, member ...	Human	HEK293 Cells
	OX40/TNFRSF4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.7 kDa and the accession number is P43489.
TMPY-01294	TNF alpha Protein, Mouse, Recombinant TNF-α,Tnfsf1a,TNF-alpha,TNF-a,Tnfa,tumor necrosis f...	Mouse	E. coli
	TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804.
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) CD252,OX-40L,tumor necrosis factor (ligand) superfa...	Human	HEK293 Cells
	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa.
TMPY-02096	TACI Protein, Human, Recombinant (His) RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor necrosis...	Human	HEK293 Cells
	TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc) Tnfcr,Lymphotoxin-beta receptor,Tumor necrosis fact...	Mouse	HEK293 Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs...
TMPY-05767	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) tumor necrosis factor receptor superfamily, member ...	Mouse	HEK293 Cells
	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.00 kDa and the accession number is P20334.
TMPY-01262	TROP-2 Protein, Human, Recombinant (His) TROP2,M1S1,GA733-1,TROP-2,GA7331,tumor-associated c...	Human	HEK293 Cells
	TROP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is P09758.
TMPY-03364	RANKL/TNFSF11/CD254 Protein, Human, Recombinant sOdf,OPTB2,TNFSF11,TRANCE,hRANKL2,ODF,OPGL,RANKL,tumor	Human	HEK293 Cells
	RANKL/TNFSF11/CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AAC51762.1.
TMPY-03674	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) sOdf,tumor necrosis factor (ligand) superfamily, me...	Human	HEK293 Cells
	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 52.4 kDa and the accession number is AAC51762.1.
TMPY-04722	DcR1/TRAILR3 Protein, Human, Recombinant (His) TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR,tumor ne...	Human	HEK293 Cells
	TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis ...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-01920	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) BAFF,THANK,BLYS,TNFSF20,CD257,tumor necrosis factor...	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-05365	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated TNFSF20,TALL-1,DTL,BLYS,THANK,tumor necrosis factor...	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is 45.6 kDa and the accession number is A0A0U5J7Q1.
TMPH-02574	p53 Protein, Mouse, Recombinant (His & SUMO) Tp53,Cellular tumor antigen p53,Tumor supp...	Mouse	E. coli
	Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex...
TMPJ-00147	FOLR1 Protein, Human, Recombinant (hFc) Folate receptor 1,Folate receptor,Folate receptor alpha,FOLR...	Human	HEK293 Cells
	FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328.
TMPH-03264	p53 Protein, Rat, Recombinant (His) Tumor suppressor p53,Tp53,Cellular tumor a...	Rat	E. coli
	Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex...
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant TNFSF15,Tumor Necrosis Factor Ligand Superfamily Me...	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPY-01166	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) TNFR80,p75,TNF-R75,TNFR1B,tumor necrosis factor rec...	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P20333-1.
TMPJ-00280	TNF R1 Protein, Mouse, Recombinant Tnfrsf1a,Tumor necrosis factor receptor superfamily...	Mouse	E. coli
	Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the...
TMPY-01185	DR5/TRAIL R2 Protein, Human, Recombinant (His) KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis fac...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
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重组蛋白

Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02975

Species: Mouse

Expression System: E. coli

Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02312

Species: Human

Expression System: E. coli

TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-05153

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-03101

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

RELT/TNFRSF19L Protein, Human, Recombinant (His)

Cat.No: TMPY-01429

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03213

Species: Rhesus

Expression System: HEK293 Cells

4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated

Cat.No: TMPY-05504

Species: Rhesus

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03645

Species: Cynomolgus

Expression System: HEK293 Cells

CD30L Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04289

Species: Cynomolgus

Expression System: HEK293 Cells

TNF alpha Protein, Rat, Recombinant

Cat.No: TMPY-02202

Species: Rat

Expression System: E. coli

TNF alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04146

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Rabbit, Recombinant

Cat.No: TMPJ-00779

Species: Rabbit

Expression System: E. coli

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00139

Species: Human

Expression System: E. coli

CD30L Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00705

Species: Human

Expression System: HEK293 Cells

Erythroferrone Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02646

Species: Mouse

Expression System: P. pastoris (Yeast)

TL1A/TNFSF15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04645

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human, Recombinant (His)

Cat.No: TMPY-05319

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Human, Recombinant

Cat.No: TMPY-00936

Species: Human

Expression System: E. coli

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-05594

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated

Cat.No: TMPY-05568

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)

Cat.No: TMPY-04493

Species: Human

Expression System: HEK293 Cells

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05376

Species: Human

Expression System: HEK293 Cells

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00033

Species: Human

Expression System: HEK293 Cells

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01743

Species: Human

Expression System: HEK293 Cells

TROP-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02667

Species: Mouse

Expression System: HEK293 Cells

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02726

Species: Mouse

Expression System: HEK293 Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00072

Species: Human

Expression System: HEK293 Cells

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

Cat.No: TMPJ-01466

Species: Human

Expression System: HEK293 Cells

HVEM Protein, Human, Recombinant (His)

Cat.No: TMPY-01750

Species: Human

Expression System: HEK293 Cells

OX40/TNFRSF4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01423

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Mouse, Recombinant

Cat.No: TMPY-01294

Species: Mouse

Expression System: E. coli

OX40L/TNFSF4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04832

Species: Human

Expression System: HEK293 Cells

TACI Protein, Human, Recombinant (His)

Cat.No: TMPY-02096

Species: Human

Expression System: HEK293 Cells

LTBR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00994

Species: Mouse

Expression System: HEK293 Cells

4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05767

Species: Mouse

Expression System: HEK293 Cells

TROP-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01262

Species: Human

Expression System: HEK293 Cells

RANKL/TNFSF11/CD254 Protein, Human, Recombinant

Cat.No: TMPY-03364

Species: Human

Expression System: HEK293 Cells

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03674

Species: Human

Expression System: HEK293 Cells

DcR1/TRAILR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04722

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04142

Species: Human

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)

Cat.No: TMPY-01920

Species: Human

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated

Cat.No: TMPY-05365

Species: Human

Expression System: HEK293 Cells

p53 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02574

Species: Mouse

Expression System: E. coli

FOLR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00147

Species: Human

Expression System: HEK293 Cells

p53 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03264

Species: Rat

Expression System: E. coli

TL1A/TNFSF15 Protein, Mouse, Recombinant

Cat.No: TMPJ-00603

Species: Mouse

Expression System: E. coli

TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)

Cat.No: TMPY-01166

Species: Human

Expression System: HEK293 Cells

TNF R1 Protein, Mouse, Recombinant

Cat.No: TMPJ-00280

Species: Mouse

Expression System: E. coli

DR5/TRAIL R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01185

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0124	Brivanib Alaninate-d4
	Brivanib Alaninate-d4 是 Brivanib Alaninate 的氘代化合物。Brivanib Alaninate 的 CAS 号为 649735-63-7。Brivanib alaninate 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐，IC50值为 25 nM，具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制，对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
TMID-0163	myo-Inositol-d6
	myo-Inositol-d6 是 myo-Inositol 的氘代化合物。myo-Inositol 的 CAS 号为 87-89-8。Inositol是一种细胞内磷酸化合物，参与细胞信号传导，可能刺激肿瘤细胞分化。
TMID-0121	DL-Homocysteine-3,3,4,4-d4
	DL-Homocysteine-3,3,4,4-d4 是 DL-Homocysteine 的氘代化合物。DL-Homocysteine 的 CAS 号为 454-29-5。DL-Homocysteine 是弱神经毒素，能够影响犬尿酸的产生。
T72818	Dosimertinib-d3
	Dosimertinib-d3是一种有效的口服活性EGFR 抑制剂。Dosimertinib-d3降低 p-EGFR 和 p-ERK 蛋白水平的表达。Dosimertinib-d3显示出抗增殖和抗肿瘤活性。Dosimertinib-d3具有非小细胞肺癌 (NSCLC) 研究的潜力。
TMID-0177	Palmitic acid-16,16,16-d3
	Palmitic acid-16,16,16-d3 是 Palmitic acid 的氘代化合物。Palmitic acid 的 CAS 号为 57-10-3。Palmitic acid 是在动物、植物和微生物中发现的最常见的饱和脂肪酸，具有抗肿瘤活性。它可诱导小鼠颗粒细胞中葡萄糖调节蛋白 78 和 CCAAT/增强子结合蛋白同源蛋白的表达。
TMIH-0025	13C-d3-AOH1996
	13C-d3-AOH1996 是 AOH1996 的 13C 和氘代化合物。AOH1996 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体，靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用，导致 DNA 复制应激，诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用，可抑制肿瘤细胞生长。
T69758	Flutamide-d7
	Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo...
T70808	Cabazitaxel-d6
	Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...
TMIH-0089	Androstenedione-d7
	Androstenedione-d7 是 Androstenedione 的氘代化合物。Androstenedione 的 CAS 号为 560-62-3。9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素，具有抗肿瘤活性，可以抑制多种癌症细胞的生长，包括乳腺癌、前列腺癌和肺癌细胞。
TMID-0003	Ribociclib-d6
	Ribociclib-d6 是 Ribociclib 的氘代化合物。Ribociclib 的 CAS 号为 1211441-98-3。Ribociclib (LEE011) 是一种细胞周期蛋白依赖性激酶 CDK4/6 抑制剂 (IC50=10/39 nM)，具有特异性和口服活性。Ribociclib 具有抗肿瘤活性，可以阻滞细胞周期，抑制肿瘤细胞增殖。
TMIH-0091	AOH-d3
	AOH-d3 是 AOH 的氘代化合物。AOH 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体，靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用，导致 DNA 复制应激，诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用，可抑制肿瘤细胞生长。
T35778	Ochratoxin A-13C20 Ochratoxin A-13C20
	Ochratoxin A-13C20is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.2Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1phase, and apoptosis in mouse ...
T71401	Oxaliplatin-d10
	Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2....
T71293	Nifuroxazide-d4
	Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...
TMID-0178	Stearic acid-18,18,18-d3
	Stearic acid-18,18,18-d3 是 Stearic acid 的氘代化合物。Stearic acid 的 CAS 号为 57-11-4。Stearic acid是长链饱和脂肪酸，存在于许多动植物油脂中。
T71055	Albendazole-d7
	Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Alben...
T69966	Roxadustat-d5
	Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...
TMID-0254	Linalool-d3
	Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。
T35915	Erlotinib-13C6 Erlotinib-13C6
	Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...
T35520	Aflatoxin G1-13C17 Aflatoxin G1-13C17
	Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase...

同位素标记化合物

Brivanib Alaninate-d4

Cat.No: TMIH-0124

Capecitabine-d11

Cat.No: TMID-0242

myo-Inositol-d6

Cat.No: TMID-0163

DL-Homocysteine-3,3,4,4-d4

Cat.No: TMID-0121

Dosimertinib-d3

Cat.No: T72818

Palmitic acid-16,16,16-d3

Cat.No: TMID-0177

Cat.No: TMIH-0025

Cat.No: T69758

Cat.No: T70808

Androstenedione-d7

Cat.No: TMIH-0089

Cat.No: TMID-0003

Cat.No: TMIH-0091

Ochratoxin A-13C20

Cat.No: T35778

Synonym: Ochratoxin A-13C20

Oxaliplatin-d10

Cat.No: T71401

Nifuroxazide-d4

Cat.No: T71293

Stearic acid-18,18,18-d3

Cat.No: TMID-0178

Cat.No: T71055

Cat.No: T69966

Cat.No: TMID-0254

Cat.No: T35915

Synonym: Erlotinib-13C6

Aflatoxin G1-13C17

Cat.No: T35520

Synonym: Aflatoxin G1-13C17

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