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ARF(26–44), cell-permeable, 是源于p14ARF肿瘤抑制蛋白的特定氨基酸序列的抗肿瘤肽。该化合物在小鼠肝细胞癌(HCC)治疗研究中作为 FoxM1(叉头框 M1 转录因子)的功能抑制剂,表现出显著的抗肿瘤效果,能有效增加肿瘤细胞的凋亡(apoptosis)并抑制肿瘤细胞的增殖及血管生成。此外,ARF(26–44), cell-permeable 同时也用于肿瘤治疗的相关研究。
ARF(26–44), cell-permeable, 是源于p14ARF肿瘤抑制蛋白的特定氨基酸序列的抗肿瘤肽。该化合物在小鼠肝细胞癌(HCC)治疗研究中作为 FoxM1(叉头框 M1 转录因子)的功能抑制剂,表现出显著的抗肿瘤效果,能有效增加肿瘤细胞的凋亡(apoptosis)并抑制肿瘤细胞的增殖及血管生成。此外,ARF(26–44), cell-permeable 同时也用于肿瘤治疗的相关研究。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | ARF(26–44), cell-permeable is an anti-tumor peptide derived from a specific amino acid sequence of the p14ARF tumor suppressor protein. It serves as an inhibitor of FoxM1, a forkhead box M1 transcription factor, and has demonstrated significant anti-tumor activity in the treatment of mouse hepatocellular carcinoma (HCC). This activity includes increasing apoptosis and reducing tumor cell proliferation and angiogenesis. ARF(26–44), cell-permeable is useful for research in cancer therapy. |
分子量 | 3585.22 |
分子式 | C149H267N69O33S |
CAS No. | 935732-44-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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