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Anti-DR5 Monoclonal Antibody
产品编号 TMAZ-0134
别名 TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5
Anti-DR5 Monoclonal Antibody is a rabbit antibody targeting DR5. Anti-DR5 Monoclonal Antibody can be used in ELISA, FACS, IF.
Anti-DR5 Monoclonal Antibody
Anti-DR5 Monoclonal Antibody
产品编号 TMAZ-0134 别名 TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5
Anti-DR5 Monoclonal Antibody is a rabbit antibody targeting DR5. Anti-DR5 Monoclonal Antibody can be used in ELISA, FACS, IF.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 811.42¥ 1,399 | 7日内发货 | |
| 50 μg | ¥ 973.24¥ 1,678 | 7日内发货 | |
| 100 μg | ¥ 1,362.42¥ 2,349 | 7日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-DR5 Monoclonal Antibody is a rabbit antibody targeting DR5. Anti-DR5 Monoclonal Antibody can be used in ELISA, FACS, IF. |
| 别名 | TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of DR5 overexpressed 293F cells with TMAZ-0134BI, followed by goat anti-rabbit IgG-ABflo 647 (red). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS, IF |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of DR5 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed: 10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | DR5 |
| 抗原种属 | Human |
| 基因ID | 8795 |
| Uniprot ID | |
| 研究领域 | Cancer Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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