Borrelidin

Name: Borrelidin
Brand: TargetMol
SKU: T10582
Price: 685 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T10582Cas号 7184-60-3

别名 Treponemycin

Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.

Borrelidin

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产品编号 T10582 别名 TreponemycinCas号 7184-60-3

Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.

规格	价格	库存	数量
500 μg	¥ 1,410	35日内发货
1 mg	¥ 2,130	35日内发货

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产品介绍

生物活性

产品描述	Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
靶点活性	CDC28-Cln2:24 μM
体外活性	Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast (IC50: 24 μM) [2]. Borrelidin is a potent angiogenesis inhibitor (IC50: 0.8 nM) and induces apoptosis of the tube-forming cells. Borrelidin has strong antimalarial activities (IC50s: 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum) [3].
别名	Treponemycin

化学信息

分子量	489.64
分子式	C₂₈H₄₃NO₆
CAS No.	7184-60-3
密度	1.1362 g/cm3 (Estimated)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

Ethanol: 100 mg/mL (204.23 mM)

溶液配制表

Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.0423 mL	10.2116 mL	20.4232 mL	102.1158 mL
5 mM	0.4085 mL	2.0423 mL	4.0846 mL	20.4232 mL
10 mM	0.2042 mL	1.0212 mL	2.0423 mL	10.2116 mL
20 mM	0.1021 mL	0.5106 mL	1.0212 mL	5.1058 mL
50 mM	0.0408 mL	0.2042 mL	0.4085 mL	2.0423 mL
100 mM	0.0204 mL	0.1021 mL	0.2042 mL	1.0212 mL