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HYDAMTIQ 是一种 PARP-1/2 抑制剂 (IC50: 29-38 nM),具有抗癌、抗炎和缺血保护作用。该化合物能够抑制肺部PARP活性,有效对抗由过敏原引起的咳嗽和呼吸困难,并减轻支气管对乙酰甲胆碱的高反应性。HYDAMTIQ 展现出广谱的抗癌活性,包括对卵巢癌、乳腺癌、前列腺癌、胰腺肿瘤以及多形性胶质母细胞瘤的抑制效果。在脑缺血、哮喘和多种癌症的动物模型中,HYDAMTIQ 已被证明具有体内效力。
HYDAMTIQ 是一种 PARP-1/2 抑制剂 (IC50: 29-38 nM),具有抗癌、抗炎和缺血保护作用。该化合物能够抑制肺部PARP活性,有效对抗由过敏原引起的咳嗽和呼吸困难,并减轻支气管对乙酰甲胆碱的高反应性。HYDAMTIQ 展现出广谱的抗癌活性,包括对卵巢癌、乳腺癌、前列腺癌、胰腺肿瘤以及多形性胶质母细胞瘤的抑制效果。在脑缺血、哮喘和多种癌症的动物模型中,HYDAMTIQ 已被证明具有体内效力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | HYDAMTIQ, a PARP-1/2 inhibitor (IC 50 : 29-38 nM), exhibits a range of pharmacological effects including anticancer, anti-inflammatory, and ischemic protective properties. It effectively reduces pulmonary PARP activity and alleviates symptoms such as allergen-induced cough and dyspnea while also diminishing bronchial hyperresponsiveness to methacholine. Moreover, HYDAMTIQ shows potent tumor suppressor activity in various cancers such as ovarian, breast, prostate, pancreatic, and glioblastoma multiforme. Demonstrating in vivo efficacy, HYDAMTIQ has been tested in animal models for conditions like cerebral ischemia, asthma, and cancer [1]. |
分子量 | 274.34 |
分子式 | C14H14N2O2S |
CAS No. | 1201832-32-7 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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