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Antitumor agent-28 is a compound that specifically targets and inhibits the activity of the ataxia telangiectasia mutated (ATM) kinase. By doing so, it effectively impedes the progression of ATM-mediated diseases and demonstrates significant anti-cancer activity.
Antitumor agent-28 is a compound that specifically targets and inhibits the activity of the ataxia telangiectasia mutated (ATM) kinase. By doing so, it effectively impedes the progression of ATM-mediated diseases and demonstrates significant anti-cancer activity.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 期货 |
产品描述 | Antitumor agent-28 is a compound that specifically targets and inhibits the activity of the ataxia telangiectasia mutated (ATM) kinase. By doing so, it effectively impedes the progression of ATM-mediated diseases and demonstrates significant anti-cancer activity. |
体外活性 | Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC 50 =7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC 50 =18 μM; HT29 cells), PI3Ka (IC 50 =0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells[1]. |
分子量 | 512.63 |
分子式 | C25H32N6O4S |
CAS No. | 2097499-67-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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